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Flocare (Fluticasone)
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Flocare

Flocare is a steroid which works by blocking the release of certain chemical messengers that cause inflammation (swelling) and irritation in the nose. Flocare is an antiallergic which relieves allergy symptoms like runny nose, watery eyes and sneezing.

Other names for this medication:
Advair, Alerflo, Cazon, Emderm, Fexin, Flocare, Floease, Flohale, Flomale, Flomist, Flovent, Fluderm, Fluster, Flutec, Fluticare, Fluticasone, Fluticone, Flutiflo, Flutilab, Flutiriv, Flutivate, Flutopic, Flutrol, Formosone, Ftica, Furamist, Furaspray, Geflute, Moliderm, Nazomac, Otrivin, Rhinofit, Sylone, Ultisone, Ventiflo, Zoflut

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Also known as: Fluticasone

Description

Flocare is a nasal spray containing fluticasone propionate. Fluticasone propionate is a corticosteroid that prevents the release of substances in the body that cause inflammation.

Flocare Nasal Spray is used to treat nasal congestion, sneezing, runny nose, and itchy or watery eyes caused by seasonal or year-round allergies.

Flocare is for use in adults and children who are at least 4 years old and is available without a prescription.

Dosage

This section provides information on the proper use of a number of products that contain fluticasone. It may not be specific to Flocare. Please read with care.

This medicine comes with patient instructions. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions.

This medicine is for use only in the nose. Do not get any of it in your eyes or on your skin. If it does get on these areas, rinse it off right away.

To use the fluticasone propionate and Veramyst® nasal spray:

When you use the fluticasone nasal spray for the first time, you must prime the spray. Press down fully the top of the pump 6 times or until a fine spray comes out. Prime the spray if it has not been used for more than 7 days (fluticasone propionate) or 30 days (Veramyst®) or if the cap has been left off the bottle for 5 days or longer. Shake the medicine well before each use. Gently blow your nose before using the spray. Tilt your head back slightly and insert the tip of the nose piece into your nostril. Close the opposite nostril with a finger. Release 1 spray and at the same time, breathe in gently through the nostril. Hold your breath for a few seconds then breathe out slowly through your mouth. Spray the opposite nostril using the same steps. Do not blow your nose or tip your head back after using the spray. Wipe the tip of the outside of the nose piece with a clean, dry tissue or cloth and put the cap back on. Throw this medicine away after you use 120 sprays.

To use the Xhance™ nasal spray:

Prime the new spray before using it for the first time. To prime, gently shake the bottle then spray 7 times into the air away from the face, or until some medicine comes out. If you have not used this medicine for 7 days or longer, prime it again by shaking and spraying 2 times into the air, away from the face. Shake the medicine well before each use. Insert the tip of the cone-shaped nosepiece deep into the nose to create a seal between the nosepiece and the nostril. Place the mouthpiece inside your mouth and blow on it. While blowing, push the bottle up to actuate the spray pump. Continue to blow through your mouth until the medicine is released, but do not inhale or exhale through the nose. Repeat in the other nostril for a full dose.

You may need to use this medicine for a few days before you start to feel better.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For nasal polyps: For nasal dosage form (spray): Xhance™: Adults—At first, 1 spray (93 micrograms [mcg]) fluticasone in each nostril two times a day. Some patients may need 2 sprays in each nostril two times a day. Your doctor may adjust your dose as needed. Children—Use and dose must be determined by your doctor. For symptoms of hay fever: For nasal dosage form (spray): Fluticasone propionate: Adults—At first, 2 sprays in each nostril once a day. Some patients may need 1 spray in each nostril two times a day (morning and evening). Your doctor may adjust your dose as needed. Children 4 years of age and older—At first, 1 spray in each nostril once a day. Some patients may need 200 mcg or 2 sprays in each nostril once a day. Children younger than 4 years of age—Use is not recommended. Veramyst®: Adults and children 12 years of age and older—At first, 2 sprays in each nostril once a day. Your doctor may decrease your dose to 55 mcg or 1 spray in each nostril once a day. Children 2 to 11 years of age—At first, 1 spray in each nostril once a day. Your child's doctor may need to increase the dose up to 2 sprays in each nostril once a day depending on your child's condition. Children younger than 2 years of age—Use and dose must be determined by your doctor.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

An overdose of Flocare is not expected to produce life threatening symptoms. Long term use of steroid medicine can lead to glaucoma, cataracts, thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.

Storage

Store at a room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw the medication away after you have used 120 sprays, even if there is still medicine left in the bottle. Keep out of the reach of children.

Side effects

The most common side effects associated with Flocare are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of fluticasone nasal spray in children. However, safety and efficacy of Veramyst® nasal spray have not been established in children younger than 2 years of age, and fluticasone propionate nasal spray in children younger than 4 years of age.

Appropriate studies have not been performed on the relationship of age to the effects of Xhance™ nasal spray in the pediatric population. Safety and efficacy have not been established.

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On this background the author briefly summarizes proven and potential adverse effects on health. Structural changes of Escherichia coli ferric uptake regulator during metal-dependent dimerization and activation explored by NMR and X-ray crystallography. Determination of k(cat)/K(m) revealed that the enzyme hydrolysed methyl sinapinate 6, 21 and 40 times more efficiently than methyl ferulate, methyl coumarate and methyl caffeate, respectively. Traditionally, the security of medical records has been based on physical lock and key. Corrosion behavior of pure titanium and titanium alloys in various concentrations of Acidulated Phosphate Fluoride (APF) solutions. Posterior scleritis is a granulomatous inflammation occurring either within the scleral tissue or in the vascular networks adjacent to it. Real-time reverse transcriptase-polymerase chain reaction of matched normal/tumor pairs confirmed higher FSH-R mRNA expression in PCa. Polymerase chain reaction disclosed the presence of an HTLV-I tax sequence in the peripheral blood.

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The measurement showed a middle anterior chamber depth of 3.42 mm preoperatively and 3.67 mm postoperatively. The protective airway mechanisms were blunted by this drug, resulting in aspiration, hypoxia, seizures, and death. Insertion of trocars at a narrow angle to the abdominal wall may cause larger fascia defects than the actual size of the trocar. Application of image processing techniques to gamma-angiography. The results indicate that the cytochrome does not form a CO complex in situ but reacts with O2, either directly or indirectly. MR is an important transcriptional regulator of macrophage phenotype and function. Differential inclusion of infected women in sero-surveys compared to uninfected women was taken into account, with respect to both changes in inclusion rate following infection, and klonopin 0.25 mg changes in relative inclusion rate over calendar time. At variance with platelet alpha IIb beta 3 or endothelial cell alpha v beta 3 integrins, CD11b/CD18 interacts with a approximately 30-kDa plasmic fragment D (D30) of fibrinogen that lacks the Arg-Gly-Asp sequences in the A alpha chain and the carboxyl terminus of the gamma chain. In patients with AF and severe underlying heart disease, the management is primarily directed at the underlying heart disease, supplemented with rate-controlling measures, and prevention of thromboembolic complications. The importance of effective triage and the deleterious effects of deviation from protocols are underscored.

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Serum levels were lower in black patients than in white patients. Immunofluorescent staining revealed an overall increase of alpha- and beta-tubulin levels in Pac-10 cells compared with DU-145 cells. Transformations describing prostate movement were measured independently of those describing setup variations of the pelvic girdle. Volatile compounds released from germinating beans such as 4-hydroxy-4-methyl-2-pentanone, 1-hepten-3-one, 1-octen-3-ol, and 3-octanone should be considered as key compounds that mediate oviposition behavior. Adults with AD had higher plasma insulin vs normal adults at the two higher infusion rates, despite receiving comparable amounts of insulin. Not the perfect study, but helpful wisdom for treating asthma patients with gastroesophageal reflux disease. For clarification of possible platelet activation in migraine and chronic muscle contraction headache (MCH) under stress, plasma platelet factor 4 (PF4), norepinephrine (NE), and free fatty acids (FFA) were investigated during the cold pressor test. Although estrogen is important in human skeletal homeostasis, the major target cell in bone is unknown.

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