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Cordalat (Nifedipine)
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Cordalat

Cordalat is a dihydropyridine calcium channel blocker. Cordalat is used to: treat high blood pressure (hypertension), prevent chronic stable angina (chest pain). Cordalat was the first calcium channel blocker to be shown to significantly reduce the development of new overt heart failure in patients with coronary artery disease. Excellent blood-pressure control in recent clinical trials has been shown to result in significant protection against stroke. Cordalat works by opening up blood vessels in the body to lower blood pressure and improve the supply of blood and oxygen to the heart. Calcium channel blockers do not change the amount of calcium in your blood or bones.

Other names for this medication:
Antrolin, Buconif, Calcheck, Calcianta, Cardiosol, Casanmil, Chronadalate, Depicor, Herlat, Macorel, Nidipine, Nifatenol, Nifecor, Nifedalat, Nifedel, Nifediac, Nifedical, Nifedigel, Nifedine, Nifelat, Nifical, Nipidin, Noviken, Nycopin, Nyefax, Vasdalat

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Also known as: Nifedipine

Description

Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Cordalat PA 10. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.

Overdose

If you overdose Cordalat and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Cordalat dosage information

Side effects

The most common side effects associated with Cordalat are:

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Contraindications

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Survey of personal protection measures against mosquitoes among Australian defense force personnel deployed to East Timor. We demonstrate marked phenotypic and genotypic differences between primary human tumor-derived TSCs and their matched glioma cell lines. Brain imaging studies demonstrate that sleep deprivation reduces glucose metabolism and blood flow in the prefrontal cortex, and such reductions are associated with impairments in cognitive functioning. We therefore studied the effects of metabolic acidosis, with and without normalization of pH by hyperventilation, on pulmonary gas exchange in dogs with permeability pulmonary edema. Impaired plasma FFA oxidation imposed by extreme CHO deficiency in contracting rat skeletal muscle.

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Alsterpaullone, a novel cyclin-dependent kinase inhibitor, induces apoptosis by activation of caspase-9 due to perturbation in mitochondrial membrane potential. Interpersonal separations and difficulties regarding discipline or the law were common recent stressors among the alcohol abuse victims, and interpersonal conflicts and somatic illness among those with depressive disorders. Cholinergic regulation of cataplexy in canine narcolepsy in the pontine reticular formation is mediated by M2 muscarinic receptors. The present study characterizes expression of calbindin D28K (CB-D28K) and parvalbumin (PV) in ventral forebrain (VFB) grafts placed in the neocortex of adult rats bearing quisqualic acid lesions to the nucleus basalis magnocellularis. Effects of change in position and ambient temperature on blood ADH levels. Extracellular currents alter gap junction intercellular communication in synovial fibroblasts.

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Relation between age and hair strontium in a population from the Dalian District of China. Our previous results showed that regulatory RNAs can induce the production of interleukin-1, interleukin-2, interleukin-8, tumor necrosis factor-alpha (TNF-alpha), interferon-gamma, and Fas ligand (FasL). luteus cells contains repair functions for oxygen methylated pyrimidine residues present in alkylated DNA. Recently, it has been demonstrated that bacteria can be characterized using whole cells and matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS). Nevus counting as a risk avelox tab 400 mg para que sirve factor for melanoma: comparison of self-count with count by physician. The control of intracellular Na in maturing oocytes of Rana temporaria. Neonatal treatment of male rats with a gonadotropin-releasing hormone antagonist results in altered function of the pituitary-testicular axis in adult age.

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Apolipoprotein B metabolism in homozygous familial hypercholesterolemia. It is now widely recognized that comprehensive cardiac rehabilitation has substantial benefits in patients with cardiovascular disease. Continuous intravenous intradialysis versus intravenous postdialysis erythropoietin therapy in chronic haemodialysis patients: a randomized, controlled, crossover study. The combined use of two parental variables, reported soft drink consumption and abscess history, appears promising for caries prediction. A pediatric surgery study: parent usage of the Internet for medical information. We illustrate these tools by analysing the results of a model of groups moving under the duress of certain informed indistinguishable individuals, that arises in the context of honeybee (Apis mellifera) swarming behaviour. Distress syndromes are common, but classifications fail to differentiate syndromes relevantly. In conclusion, embryos acquire the ability to undergo thermotolerance as they progress through development.

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A variety of compounds with a common noradrenergic/dopaminergic activity have shown documented anti-Attention-Deficit/Hyperactivity Disorder (ADHD) activity. The promotion of competency of nurses and other health-care professionals is a goal shared by many stakeholders. The retrospective analysis of 250 breast cancer patients with disseminated disease provided evidence that the increase in CA 125 serum levels in these patients was caused by lung metastases or pleural effusions. Resting T cells as well as blast T cells were periactin pills sensitive to this inhibitory effect of CsA. Dopaminergic receptor agents and the basal ganglia: pharmacological properties and interactions with the GABA-ergic system.

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