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Alpronit (Alprazolam)

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Alpronit is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alpronit, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alpronit is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alamflu, Altin, Altrex, Anxicalm, Anxorel, Anzocalm, Balmusa, Cooltime, Cozac, Dazolam, Eurolam, Fludep, Fluwel, Fluxozam, Indolam, Maxorest, Mediprex, Proprazolam, Riolam, Sinaday, Sowel, Sozox, Synozolam, Tenrid, Tranax, Tranisol, Trapose, Trika, Unixl, Zallpam, Zeecam, Zepro, Zoltweet, Zopax

Similar Products:
Retin, Fasigyn, Vermox, Ultram, Valium, Robaxin, Zyprexa, Panadol, Naprilene, Alicante, Openvas, Firin, Lapikot, Oncomide, Diamin, Losaprex, Arilan, Zitroken,

Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


Usual Adult Dose for Anxiety:

Immediate-release tablets: 0.25 to 0.5 mg orally administered 3 times a day -Maximum dose: 4 mg/day

Usual Adult Dose for Panic Disorder:

Immediate-release tablets: 0.5 mg orally administered 3 times a day -Maximum dose: 10 mg/day Extended-release tablets: -Initial dose: 0.5 to 1 mg orally once a day -Maintenance dose: 3 to 6 mg orally per day, preferably in the morning -Maximum dose: 10 mg/day Comments: -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage. -The daily dosage may be decreased by no more than 0.5 mg every 3 days; however, some patients may require an even slower dosage reduction. -The dose of extended-release tablets may be increased at intervals of 3 to 4 days in increments of no more than 1 mg per day. -The times of administration should be distributed as evenly as possible throughout the waking hours.

Usual Geriatric Dose for Anxiety:

Elderly or debilitated patients: Immediate-release tablets: 0.25 mg orally administered 2 or 3 times a day.

Usual Geriatric Dose for Panic Disorder:

Elderly or debilitated patients: Immediate-release tablets: -Initial dose: 0.25 mg orally administered 2 or 3 times a day Extended-release tablets: -Initial dose: 0.5 mg orally once a day Comments: -If side effects develop, the dose may be lowered. -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage.

Detailed Alpronit dosage information


If you have been prescribed Alpronit for medical reasons, the best way to avoid a Alpronit overdose is to adhere to prescribed orders—closely monitor your dose and the time at which you take your medication. Track your Alpronit consumption in a notebook or on your phone. If you notice that you are taking a higher dose of the drug, taking the drug more often, or you want to consume more of the drug, talk with your doctor immediately.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Alpronit are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not use Alpronit XR if you have:

narrow-angle glaucoma; if you are also taking itraconazole (Sporanox) or ketoconazole (Nizoral); or if you are allergic to alprazolam or to other benzodiazepines, such as chlordiazepoxide (Librium), clorazepate (Tranxene), diazepam (Valium), lorazepam (Ativan), or oxazepam (Serax).

Before taking Alpronit XR, tell your doctor if you are allergic to any drugs, or if you have:

asthma, emphysema, bronchitis, chronic obstructive pulmonary disorder (COPD), or other breathing problems; glaucoma; kidney or liver disease (especially alcoholic liver disease); a history of depression or suicidal thoughts or behavior; or a history of drug or alcohol addiction.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

It is dangerous to try and purchase Alpronit XR on the Internet or from vendors outside of the United States. Medications distributed from Internet sales may contain dangerous ingredients, or may not be distributed by a licensed pharmacy. Samples of alprazolam purchased on the Internet have been found to contain haloperidol (Haldol), a potent antipsychotic drug with dangerous side effects. For more information, contact the U.S. Food and Drug Administration (FDA) or visit

FDA pregnancy category D. Alpronit XR can cause birth defects in an unborn baby. Do not use Alpronit XR without your doctor's consent if you are pregnant. Tell your doctor if you become pregnant during treatment. Use an effective form of birth control while you are using this medication. Alprazolam can pass into breast milk and may harm a nursing baby. Do not use Alpronit XR without telling your doctor if you are breast-feeding a baby.

The sedative effects of Alpronit XR may last longer in older adults. Accidental falls are common in elderly patients who take benzodiazepines. Use caution to avoid falling or accidental injury while you are taking Alpronit XR. Do not give this medication to anyone under 18 years old.

Alpronit XR pregnancy and breastfeeding warnings (more detail)

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This study has potential applications in human performance modeling and assessment of mental workload, such as the design of training materials and interfaces for those performing complex multitasking under stress. Based on primary survey data from 209 front-line workers in one of the largest state-owned coal mining corporations in China, the model is tested using structural equation modeling techniques. Some data suggest that we should not use an unnecessary and high dose of opioid without clear indication. To review the effectiveness of, and make practice recommendations for, serial clinical examination and ultrasound screening for developmental dysplasia of the hip (DDH) in newborns. The ridge cross section was designed to permit only the fundamental mode to be excited during operation of the motor, with a Langevin transducer used as the source of vibration in this study.

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Its antimicrobial activity is due to damaging cellular macromolecules. Clozapine in medication- and electroconvulsive therapy-resistant, depressed inpatients: a case series. Perspectives on the selection, training, roles, achievements and challenges of the SMAG programme were explored. Dental caries experience among 12-year-old children in the Gaza Strip. Spurious polycythemia patients with high blood pressure as a complication have a high possibility of developing cerebral vascular disease.

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Cryoablation in fibro-adipose vascular anomaly (FAVA): a minimally invasive treatment option. Kinetic studies of the interaction between rifampicin and DNA-dependent RNA polymerase of Escherichia coli. Treatment of yeast cells with 0.2-0.6mM NiCl(2) resulted in reduced expression of the URA3 gene as assessed by increased resistance to 1g/l 5-fluorotic acid (5-FOA). Although multiple co-occurring chronic illnesses within the same individual are increasingly common, few studies have examined the challenges of multimorbidity from the patient perspective. Oxazolidinone antibacterial agents, where the N-substituted piperazinyl group of eperezolid was replaced with a N-substituted piperidinyloxy moiety, were synthesized and shown to be active against a variety of resistant and susceptible Gram-positive organisms. We included consecutive patients presenting to a US emergency department with serial cTnI onclinical indication. Skin morphological changes in growth hormone deficiency and acromegaly.

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The data provide some support for the use of EQ-5D when interviewer administered. Histone deacetylase inhibitors (HDACIs) can inhibit cell proliferation, induce cell cycle arrest, and stimulate the apoptosis of cancer cells. It is intended to stimulate the development of skills in scientific thinking by allowing the student, in a self-directed fashion, to design a clinical trial to test either a given hypothesis (specific deck) or a hypothesis that the player provides (general deck). Recently, efficient disposal of food waste (FW) with potential resource recovery has attracted great attentions. The results showed that with most of the modifications of the Boyden method in use at present, the choice of incubation time is crucial for the evaluation of counting results. These findings suggest that it is feasible to obtain assessments from professional associates of practicing physicians in areas such as clinical skills, humanistic qualities, and communication skills. Thirteen paid student volunteers (9 male, 4 female) were used in a double-blind crossover experiment to investigate the effects of a therapeutic dose of dexchlorpheniramine alone, and in combination with a social dose of ethanol on perceptual, cognitive and motor functions. Characterization of new monoclonal antibodies identifying avian T lymphocyte antigens.

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All women over the age of 15, who visited any of 50 health centres in different districts for different purposes, were asked to participate in the study. These in vitro experiments showed a good correlation between timed volume collections and electromagnetic flow assessment up to high flow velocities. This study investigated the expression of SKIP and its potential clinical and biological significances in hepatocellular carcinoma (HCC). Affordable Care Act provisions aimed at increasing access to insurance and primary care can potentially align the consumption patterns of US- and foreign-born disabled working-age adults. As examples of our prescription, we analyze numerically three nonequilibrium systems that annihilate cluster of particles that are identified as conserved versions of the pair annihilation contact model, triplet annihilation contact model, and pair contact process. The patient recovered fully from the closed space bacterial infection without additional surgical drainage. Missing in action: Species competition is a neglected predictor variable in species distribution modelling. Two case illustrations were also provided for clinical application.

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The dosimetric outcomes of radiograph- and computed tomography-based plans generated with various optimisation strategies were compared using dose volume indices for partial breast intraoperative implants. Rapidly, left atrium (LA) collapse associated with hemodynamic compromise occurred without any pericardial effusion. Communication on the significance of surface-active substances in the manufacture of medicinal preparations. The resulting populations (between 41 and 301 independent plants for each construct) were assayed for trait formation. Acute exercise enhances nitric oxide modulation of vascular response to phenylephrine. IL-1beta-induced aggrecan breakdown was followed by a rise in(35)S-aggrecan metabolites in the incubation media of the cells in culture. Stage-dependent analgesia of electro-acupuncture in a mouse model of cutaneous cancer pain. Despite the wide numbers of papers on this topic, there are still several open questions about pathogenesis, epidemiology, natural history and prognosis. Photochemical generation and decay kinetics of superoxide and hydrogen peroxide in the presence of standard humic and fulvic acids. The first MCL-1-selective BH3 mimetics capable of high-affinity binding and inducing apoptosis in cancer cells through an on-target mechanism have just been identified.

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Eight types of DORV were established: type I (normal relation, committed VSD, without POTO), type II (normal relation, committed VSD, POTO), type III (normal relation, remote VSD, without POTO), type IV (normal relation, remote VSD, POTO), type V (abnormal relation, committed VSD, without POTO), type VI (abnormal relation, committed VSD, POTO), type VII (abnormal relation, remote VSD, without POTO), type VIII (abnormal relation, remote VSD, POTO). The localization of PARP-1 in chromatin and its enzymatic activation involves multiple interactions of PARP-1 with nucleosomal histones, other proteins, and DNA. The combination therapy also attenuated LV dilation, as compared with ES cell-derived cardiomyocyte transplantation alone. The chordal cutting technique was described first in experimental studies by Messas et al. In a population of refractory IBD patients with recent malignancy, anti-TNF could be used taking into account a mild risk of incident cancer.

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The primary endpoint was the antihypertensive effect of each regimen. Blue light also failed to induce negative phototropism in pks1 under reduced gravitational stimulation, indicating that the effect of pks1 on phototropism is not simply the consequence of the counteracting effect of enhanced gravitropism. The relationship of individual continuous factors to the development of CAD and CVD as well as multivariate models were evaluated with use of the Cox proportional hazards model. We have applied the model to solid/solid and solid/fluid interfaces with arbitrary Atwood numbers. Also, cloacal swabs were taken from 100 carcasses of graylag geese shot during the hunting season in August. In the present study, we tried to assess the neuroprotective effects of telmisartan and nimodipine (TM-NM) combination on the secondary reperfusion phase. Design of Finasteride-Loaded Nanoparticles for Potential Treatment of Alopecia. Anticipatory coarticulation and stability of speech in typically fluent speakers and people who stutter. The relationship between insulin action and hypertriglyceridaemia on endothelial function is still debated. An obvious decrement of FPV for patients with normal LV systolic function was noted, but no obvious difference was seen for patients with abnormal LV systolic function.

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We collected follow-up data on surgeries and development of CRC from hospital and community medical records or via direct contact with patients during a median time period of 14 years. To describe characteristics of acute poisoning with liquid ecstasy (gammahydroxybutyrate, GHB). NaCl effects on protein and chlorophyll concentrations were greater in P-deficient medium, while presence or absence of P in the medium had little effect on cellular carbohydrate concentrations. Wires E27, RF and R had the highest moments during activation and deactivation, without evidence of the plateau typical of the superelastic effect. In contrast to the studies terminated at shorter times, the degree of protection furnished by the use of dithiocarbamates at longer times post-treatment is less impressive. With this method established, the versatility and applicability of HSDFM are greatly enhanced.

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Uraemic peripheral neuritis persisting after renal transplantation. Even a relatively large trial in which more information on treatment efficacy on the basis of mRS scores is collected would represent good value for information. Our results also confirmed some of our assumptions but religion did not have the expected influence. General approaches to creating regioselective reagents are outlined, that can be widely used for modification of both proteins and nucleic acids. These data may provide increased insight on long-term prognosis and inform clinical decision-making by identifying subgroups of cancer survivors who may benefit from rehabilitative intervention.

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Acquired amnestic aphasia after roentgenotherapy in a 7-year-old child. Quality Assessment of the Ethics Consultation Service at the Organizational Level: Accrediting Ethics Consultation Services. Early-life family income and subjective well-being in adolescents. Intraperitoneal administration of 0.2, adalat cc dosing 1.0 or 5.0 mg DNP/kg b.w. An attempt is made to define and evaluate these problems and to show, with reference to selected examples, what measures have been and are being implemented to overcome them.

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Active healthy elderly women do not have a better nutritional profile than their inactive peers. Dientamoeba fragilis is a gastrointestinal protozoan that has a worldwide distribution and is emergeing as a common cause of diarrhea. To evaluate structures involved in pelvic support using conventional and snapshot magnetic resonance imaging (MRI). A critical intersection: human rights, public health nursing, and nursing ethics. Thus binding cozaar 50 mg dosage of the Gal4 activator to target sites in the DNA is required but not sufficient for GAL2 derepression and induction. The current-voltage characteristics show some nonlinear features but are not greatly affected by the hydrodynamic flow in the parameter regime studied. Evidence for catabolite degradation in the glucose-dependent inactivation of yeast cytoplasmic malate dehydrogenase. Recent evidence has implicated p56lck in a critical role both in T cell development and activation. The use of the nasocheek sulcus flap with a cartilage strut provides an aesthetically pleasing result in total columella reconstruction.

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The maxillofacial injury associated with multiple trauma: a prospective study of diagnostic miss in fractures. Lastly, abnormalities in chromosomes inheritance leading to aneuploid formation were revealed using microsatellite analyses in the offspring from the controlled cross in subsp. Moreover, several naturally or food proteins-derived bioactive peptides that could prolong the activated partial thromboplastin time (APTT) and thrombin time (TT) have been isolated. The aim of this study was to investigate factors influencing the prognosis of patients with RGC. Treating severe spasticity with the continuous infusion of intrathecal baclofen through an implantable delivery system is a new and successful alternative to oral medications and ablative surgical procedures. Descriptive cross study, held in 2015 with 638 students at the Health Sciences Center of the Federal University of Santa Maria, State of Rio Grande do Sul, Brazil. Some etiological aspects of vegetovascular dysfunction with hypotensive type in children. Role of the functional independence of the right and left hemisections. epidermidis induced high levels of IL-1 alpha, IL-1 beta, and TNF alpha in 24-h-conditioned medium.

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Analysis of nursing home files for five study periods, each lasting 6 months. Easily accessible and handled ether-imidazolium chlorides were developed as ligand precursors. Baseline predictors of response to divalproex in conduct disorder. The findings suggest that the analgesic effect following DHC ingestion is mainly attributed to the parent drug rather than its DHM metabolite. Formulation and evaluation of diazepam hydrogel for rectal administration.

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Putative identification of the usnic acid biosynthetic gene cluster by de novo whole-genome sequencing of a lichen-forming fungus. An initial investigation of bottleshops, which included an observational study designed to analyse methods employed by the liquor industry to market RTDs in bottleshops, on the central coast of New South Wales. Commissioning is set to become a stronger feature in the Australian health system as Primary Health Networks embrace it as a tool for improving population health outcomes. To determine the mechanism of bradykinin degradation in the coronary circulation of the rabbit, using an isolated perfused heart preparation. Laboratory tests, such as blood counts, blood glucose, and electrolyte panels (particularly sodium), lumbar puncture, and toxicology screening may be helpful as determined by the specific clinical circumstances based on the history, physical, and neurologic examination, but there are insufficient data to support or refute recommending any of these tests for the routine evaluation of adults presenting with an apparent first unprovoked seizure (Level U). Ballistic gelatin is the most common tissue simulant used to reproduce the penetration of projectiles into muscle but published data to support its use are primarily based on bullets, despite explosive fragments being the most common cause of injury to soldiers on current operational deployments. A second-level review focused on particular aspects of the modelling process through case study assessments of screening models for three specific disease areas (colorectal cancer, abdominal aortic aneurysms and antenatal screening for haemoglobinopathies). The crucial aspects of the G-DRG version 2005 and the accompanying rules and regulations of payment are reviewed in detail with special relevance to dermatology. At the age of 12 days, one group was inoculated intra-ocularly with 10(3) EID 50 of the 793/B isolate, and the other was kept as the control group ceclor 750 generic name . Evolutionary ecotoxicology of wild yellow perch (Perca flavescens) populations chronically exposed to a polymetallic gradient.

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In this paper, the authors describe the clinical, morphological, immunohistochemical features and surgical treatment of a case of primary oral mucosal melanoma with osteocartilaginous differentiation and they review the existing literature. Every 36-h gentamicin dosing in neonates with hypoxic-ischemic encephalopathy receiving hypothermia. By requiring or encouraging enrollees to obtain a usual source of care, managed care programs hope to improve access to care without incurring higher costs. The induction is independent of nitric oxide or reactive oxygen species but does involve protein kinase C and phospholipase A2. The electroencephalogram, obsessional illness and obsessional personality. Physician organizations in California broke new ground in the 1980s by accepting capitated contracts and taking on utilization management functions. The Good, the Bad, and the Ugly of Using Left Ventricular Longitudinal Myocardial Deformation by Speckle-Tracking Echocardiography to Assess Patients After an Acute Myocardial Infarction. HPV16, 52, 58 were the major genotypes among the study population. The products of this biotransformation were identified as tetrachlorocatechol and 2-methoxy-3,4,5,6-tetrachlorophenol by comparing mass spectra recorded elavil 25 mg side affects before and after n-butylboronate and N,O-bis(trimethylsilyl)-trifluoroacetamide derivatization with those of authentic compounds.

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Interrelation of vasomotor rhinitis and asthma, occurring in patients with housedustatopy. The use of ice as a supplement to an exercise programme has been recommended for the management of lateral elbow tendinopathy (LET). It is thus a good indicator of quality, but also a training tool, and has a significant impact in the grieving process. Eliminating tobacco-related disparities among Pacific Islanders through leadership and capacity building: promising practices and lessons learned. Metal-Mediated Addition of N-Nucleophiles to Isocyanides: Mechanistic Aspects. In view of the clinical trials for HPV vaccine taking place in India, it is of utmost importance to understand the prevalence of HPV genotypes in various geographical regions of India. PrP biochemical properties are also strain-dependent, such as different digestion pattern after proteolysis and different stability.

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Evaluating the effects of e-cigarettes among khat chewers could be important in understanding the impact of e-cigarettes as a harm reduction approach, with the potential to reduce the health risk associated with smoking. The duration of survival after unilateral allogenic lung transplantation is reported, although this is no direct scale for the technical performance. Observations on criminal and civil law responsibilities in the nursing profession. Both NS-398 and indomethacin to much the same extent significantly decreased prostaglandin E2 (PGE2) contents in inflammatory tissue. Chromomycin A3 was administered iv to 26 patients in a phase I trial. While water/dodecane features a mechanism of sheer competitive adsorption at the interface, separation in water/1-butanol is mainly due to partitioning into both liquid phases, leading to a higher degree of separation. Resonant dynamic Stark shift as a tool in strong-field quantum control: calculation and application for selective multiphoton ionization of sodium.

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In acute lymphoid leukemia mainly the bcr-abl, and in acute myeloid leukemias, depending on the morphological classification, the aml-eto, bcr-abl, pml-rara, plzf-rara, and cbfb-myh chimeras were investigated. Only in cases of minimal reflections does FWA primarily reveal the interaction between peak aortic flow and proximal aortic diameter/stiffness. Urgent public health interventions are required to prevent its development by controlling the cardiometabolic risk factors associated with it. Pooled normal AH was spiked with six cytokines at decreasing concentrations for evaluating the CBA. The linear calibration plots between fluorescence intensity and TPP concentration are determined in the 1.14 x 10(-8)-5.06 x 10(-6) mol l(-1) range. Ten patients having the lower body lift alone or in combination with liposuction and other body contouring procedures were followed for 6 to 24 months. Breast cancer resistance protein (BCRP) is expressed in various tissues, such as the gut, liver, kidney and blood brain barrier (BBB), where it mediates the unidirectional transport of substrates to the apical/luminal side of polarized cells. Quantitative measurement of CT scan images confirmed clinically observed findings in these patients before suture release and reconstruction and proved useful in assessing the surgical results achieved.

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The orientation of the absorption dipole of the dye with respect to the axis of F-actin was calculated from polarization of fluorescence which was measured by a novel method from video images of muscle. Cyclin and cyclin-dependent kinase 1 mRNA expression in models of regenerating liver and human liver diseases. Steroid-free maintenance immunosuppression after heart transplantation. We introduce for the first time, to the best of our knowledge, a three-dimensional experimental joint transform correlator (JTC) cryptosystem allowing the encryption of information for any 3D object, and as an additional novel feature, a second 3D object plays the role of the encoding key. The purpose of this study was, first, to investigate impairments in glenohumeral and scapulothoracic strength and in abduction and internal rotation ROM in patients with SIS. Cysticerci can lodge themselves in any part of the ocular and extra ocular tissue. The purpose of this prospective study was to determine the feasibility and accuracy of high-spatial-resolution MR imaging at 3 Tesla (T) in the preoperative evaluation of potential living related kidney donors.

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