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Alprine (Alprazolam)

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Alprine is commonly used to treat anxiety and panic disorders. It falls into a category of medications called benzodiazepines. They are known to affect the central nervous system components and produce a calming effect, thus decreasing brain activity.

Other names for this medication:
Aldep, Aldip, Almee, Alpam, Alpraday, Alpram, Alpramax, Alprastan, Alprose, Altok, Alzoax, Ambusyn, Anxicalm, Apsolam, Aryalam, Coolam, Enxolam, Esteem, Fledore, Fludep, Hiprazole, Imprax, Morecalm, Pacyl, Pifzot, Plxna, Poize, Pyrex, Samrox, Silam, Somnia, Tancalm, Tenan, Tenlax, Tensyn, Trapose, Trustin, Viprax, Zenax, Zolar, Zolark, Zopain, Zorest

Similar Products:
Zocor, Persantine, Bystolic, Xalatan, Ativan, Suhagra, Losaprex, Zendol, Espauz, Calosto, Xartan, Esoper, Verelan, Makrodex, Nurogab,

Also known as: Alprazolam


Alprine XR (alprazolam) is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). Alprazolam affects chemicals in the brain that may become unbalanced and cause anxiety.

Alprine XR is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

Alprine XR may also be used for other purposes not listed in this medication guide.


Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results.

Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time.

Measure the liquid form of Alprine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Do not swallow the orally disintegrating tablets whole. Allow it to dissolve in your mouth without chewing.

Contact your doctor if this medicine seems to stop working as well in treating your panic or anxiety symptoms.

You may have seizures or withdrawal symptoms when you stop using Alprine. Ask your doctor how to avoid withdrawal symptoms when you stop using Alprine.

Keep track of the amount of medicine used from each new bottle. Alprine is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.


If you have been prescribed Alprine for medical reasons, the best way to avoid a Alprine overdose is to adhere to prescribed orders—closely monitor your dose and the time at which you take your medication. Track your Alprine consumption in a notebook or on your phone. If you notice that you are taking a higher dose of the drug, taking the drug more often, or you want to consume more of the drug, talk with your doctor immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alprine dosage information

Side effects

The most common side effects associated with Alprine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Avoid drinking alcohol. Dangerous side effects or death could occur.

Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

Grapefruit may interact with alprazolam and lead to unwanted side effects. Avoid the use of grapefruit products.

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AMPK is a key enzyme in maintaining metabolic homeostasis and has been implicated in the activation of autophagy in distinct tissues. The epithelial cell adhesion molecule (EpCAM) is expressed by most epithelia and is involved in processes fundamental for morphogenesis, including cell-cell adhesion, proliferation, differentiation, and migration. End-tidal carbon dioxide (EtCO2) is a valuable marker of the return of adequate circulation after cardiac arrest due to medical causes. According to the model of this study, particles of intermediate size seem to bear highest potential to act as hazardous substances. A comparative review of methods for T cell depletion in the prophylaxis of graft-versus-host disease. CRT improves the exercise capacity and functional reserve of the failing heart through enhancing the cardiac flow- and pressure-generating capacity. Pulmonary artery smooth muscle cell (PASMC) adhesion, spreading, and migration depend on matrix-stimulated reorganization of focal adhesions. Diagnosis is based on clinical symptoms as well as radiologic and endoscopic findings. Neurological outcome was evaluated using the modified neurological severity score.

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One class of mutations, which map between the b538 and bio386 endpoints, does not appear to be associated with any major chromosomal modification, whereas the second class has the IS2 insertion sequence in orientation II within the region between gene int and the b538 endpoint, All int-c mutations are within gene xis, with the possible exception of int-c548, which might be located between int and xis. Among a population of women treated with breast-conserving surgery and radiation for DCIS, additional (boost) radiation was not associated with a lower risk of local or invasive recurrence. The trial took place in a day surgery unit with patients who were having a range of surgical procedures including hernias and varicose veins. Given a Voronoi diagram, the proposed algorithm transforms the atomic structure to meshes which contain the information of the proximity among atoms, and then recognizes depressions on the surface of a protein using the meshes. Dopamine agonist (DA) therapy is recommended as the first-line treatment for prolactinomas. In this paper, we describe a novel deep convolutional neural network (CNN) that is deeper and wider than other existing deep networks for hyperspectral image classification. Overall, our results suggest that understanding how individuals perceive risk is vital to understand the behavior of attackers. Surgical extirpation of the tumor restores the normal cerebrospinal fluid circulation at the foramen magnum and produces an excellent outcome. Development of venous collateral circulation allowed for normal function of the liver graft. Brugada-like electrocardiographic pattern: a challenge for the clinician.

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Patients transferred from these hospitals may give rise to a spread of MRSA in Scandinavian hospitals, where MRSA only occur sporadically. Embedded vertically aligned cadmium telluride nanorod arrays grown by one-step electrodeposition for enhanced energy conversion efficiency in three-dimensional nanostructured solar cells. Piotrowski: Award for Distinguished Professional Contributions: 1980. Depending on their size and site may result in mitral valve obstruction which may lead to pulmonary hypertension. The transcription factor, nuclear factor-kappa B (NF-kappaB), plays a pivotal role in regulating pro-inflammatory cytokine gene expression. An experimental annual contribution to the pathogenesis of urinary calculi. A search of the protein BLAST database revealed that this protein can be classified as a typical member of a DREB subfamily.

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Diagnosis of combined chronic poisonings with heavy metals (copper and lead, lead and mercury). Multichannel pulsatile stimulation is essential for electrotactile presentation of spatiotemporal patterns in sensory substitution through the sense of touch. In addition, emission color of the solution greatly changed so that the detection was possible even by naked eyes. Improvement of myotonia with carbamazepine in three cases with the Schwartz-Jampel syndrome. The treatment resulted in the selective cleavage of interchain disulfide bonds of the IgG to give S-sulfonate groups.

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However, there are conflicting perspectives on the roles of mosaicism and the extent to which it generates a spectrum of genome diversity8 or genetically discrete populations9,10. These seminiferous tubules were mostly composed of Sertoli cells. Both tagged constructs produce proteins of the expected molecular masses and are functional in fatty acid import assays. These improvements occur in both strength and endurance exercise. Stochastic onset but programmed completion of mammalian chromosome duplication. Molecular-sized micropores of ZSM-5 zeolite catalysts provide spatial restrictions around catalytic sites that allow for shape-selective catalysis. Ultrasound of the abdomen is an inexpensive, safe, and easy tool that can help in the differential diagnosis. The psychological morbidity, functional impairment, and disturbance in psychosocial adjustment to illness was evaluated in relation to breast cancer-related arm swelling. Transparent exopolymer particles (TEP) have been described as a class of particulate acidic polysaccharides, which are large, transparent organic particles, and commonly found in seawater, surface water, and wastewater. Currently, there is little information available concerning the results of shoulder synovectomy in patients with rheumatoid arthritis.

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: Lamotrigine previously was found to attenuate ketamine-induced behavioral changes and, in 2 placebo-controlled trials, to improve psychosis when added to antipsychotic medication. The purpose of this article is to review a large series of patients evaluated for disorders of the facial nerve in order to assess the indications for surgery, the timing of surgery, the techniques of nerve repair, and to better define those factors associated with a favorable outcome. Test-retest reliability of the soleus H-reflex in three different positions. Report of the Committee on Standard Preparation of Diphtheria Antitoxin. We describe a patient with chronic granulomatous disease and receiving immunosuppressive therapy for refractory granulomatous colitis who developed fatal fulminant pneumonia, with Trichosporon pullulans isolated from multiple sites. The experimental and computed results obtained in this study are useful to solve practical engineering problems in surface waters. Finally, HIV-2 infected MDMs display increased dNTP concentrations as predicted by Vpx-mediated SAMHD1 degradation. Advances in surgical techniques will be reviewed for both primary sites and the neck and also in the salvage settings.

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Aqueous degenerative effect and the protective role of endothelium in eye pathology. The hyperplastic effects associated with the feeding of high doses of sulfosulfuron occur only with the appearance of urinary tract calculi. Evaluation of gestational age based on ultrasound fetal growth measurements. Continuous measurement of canine coronary blood volume change with alterations of heart rate. Because the list was developed in the late 1970s, many new surgical procedures have been introduced and others improved upon, making the original MSBOS obsolete. These strategies include prompt diagnosis, timely and aggressive nutritional support, augmentation of MCC and improved mucous drainage, initiation of antimicrobial and anti-inflammatory therapy as soon as possible, early treatment of acute exacerbations, implementation of effective hygienic measures in and outside CF centers and prompt identification and treatment of CF-related complications. The students, mostly boys, who declared the regular physical activity (they most commonly practiced sports), had not abstained from alcohol, especially beer and had got drunk often. Spatial distribution of impurities in ZnO nanotubes characterized by cathodoluminescence. The properties of an ideal drug delivery system are the structural control over size and shape of drug or imaging agent cargo/domain, biocompatibility, nontoxic polymer/ pendant functionality and the precise, nanoscale container and/or scaffolding properties with high drug or imaging agent capacity features.

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These data further delineate clinical aspects of acute herpes zoster neuralgia, underline the unsolved therapeutic problems associated with this condition despite otherwise effective antiviral treatment, and characterise a subgroup of patients at risk to develop postherpetic neuralgia. Since arginine vasopressin (AVP) regulates Na-K-ATPase activity directly via protein kinase A and indirectly via hyperosmolality, we investigated the acute and chronic effects of hyperosmolality on Na-K-ATPase and AVP-dependent cAMP generation in the MAL and OMCD. Effects of swimming exercise on high-fat diet-induced low bone mineral density and trabecular bone microstructure in rats. Autophagy is an essential cellular mechanism for cell homeostasis and survival by which damaged cellular proteins are sequestered in autophagosomal vesicles and cleared through lysosomal machinery. Tuberculosis Case Finding in Institutional Populations-The Use of 35 mm. LncRNAs, a type of non-coding RNAs longer than 200 nucleotides, have been reported to interplay with SWI/SNF complex during cancer progression. Rapid rehydration of excised shoots was used as a means of differentiating the direct influences of ABA and water potential on stomatal closure. Regional and distant nodes were equally common sites of lymphoma after orchiectomy.

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We report a rare case of a 63-year-old Chinese male who presented with primary intradural extramedullary HPC of the thoracic spine. The concept of fitness varying with respect to both genotype and environment is important in models of cancer initiation and progression, bacterial dynamics, and drug resistance. Engineering a ligand binding pocket into a four-helix bundle protein cytochrome b(562). Due to the lack of reliable evidence, we are unable to draw conclusions about the benefits and harms of oral daily aspirin as an adjunct to compression in VLU healing or recurrence. Benign inoculation lymphoreticulosis: axillary suppurated adenitis and pulmonary hilar image. Most adults gamble recreationally yet few studies have systematically investigated for gender-related differences in recreational gamblers. Great cervical venous tumoral thrombosis of melanotic medullary carcinoma thyroid: Fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography enabled diagnosis and radiotherapy planning. Physiological and environmental data are also integrated in the simulation process on demand by the users. The dependence of the formation constant of the complex on the polarity of the media suggests a charge-transfer nature of the complex. Optimized distributions that conform the dose to irregularly shaped target volumes that wrap around critical structures are possible using superimposed multileaf fields.

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Derived measures included user job classification, 35 flags codifying message content, and a taxonomy grouping the flags. We comment the rich clinical expression and the peculiarities of presenting focal liver lesions and circulating anticoagulant, in a case of secondary syphilis. Conversely, treating cells with immobilized anti-immunoglobulin and interleukin 4, conditions known to prime cells, protects them from class II-mediated death and specifically from increases in nucleosomal fragments characteristic of apoptotic death. The participants were able to act as a reference group to assign the value of 12 analytes in a control serum with low concentration of most analytes. Characterization of a recombinant fowlpox virus expressing the native hexon of hemorrhagic maxolon dose medscape enteritis virus.

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By using the catalytically inactive GRK2 mutant K220R, and the receptor mutants that lack potential phosphorylation sites in the C-terminal tail, we demonstrated that the GRK2-mediated mGluR5 desensitization was phosphorylation-independent. A complication of augmentation mammaplasty is presented in which the bag of a gel-filled implant ruptured and the thin gel migrated through subcutaneous planes as far as the groin. Characterization of lymphoid cells that proliferate in response to RCS cells. This review summarizes the current evidence around biomarkers of response to PD-1/PD-L1 inhibition, considering features related to the tumor and to the host immune system. This zetia 20 mg pilot survey suggests that AORTIC members in sub-Saharan Africa continue to make gains in the provision of access to multidisciplinary breast cancer care, but the lack of adequate pathology and radiotherapy services is a barrier. Football helmets used by high school athletes in the United States should meet the National Operating Committee on Standards for Athletic Equipment performance standards. Mammographic calcification can predict outcome in women with breast cancer treated with breast-conserving surgery. Spatial normalization of brain images with focal lesions using cost function masking.

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The journey of the insulin receptor into the cell: from cellular biology to pathophysiology. Providers also were surveyed as to whether their primary EMS agency had the necessary specialty equipment to respond to these specific events. Spectrophotometric measurements of optical densities from pial veins 50-80 microns in diameter indicated that the superfusion with the allosteric compounds reduced hemoglobin oxygen saturation both during room air breathing theophylline 100mg er tablets and during hypoxia. Minimally invasive thoracic corpectomy: 3-dimensional operative video of a posterolateral approach to decompression and anterior column reconstruction. Diabetes mellitus associated with atypical antipsychotic medications: new case report and review of the literature. Osteosarcomas, chondrosarcomas, and all variants of liposarcomas and rhabdomyosarcomas over-expressed PD-1 relative to normal tissue. These results suggest that radiomics can detect early changes associated with local recurrence that are not typically considered by physicians. Xenopus serves as an experimental model to evaluate the contribution of adaptive immunity in host susceptibility to emerging ranaviral diseases that may contribute to amphibian population declines. Drug-induced respiratory depression is a common side effect of the agents used in anesthesia practice to provide analgesia and sedation.

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Structure based design of a novel class of aminopyrimidine MTH1 (MutT homolog 1) inhibitors is described. Using information-theoretic principles, I introduce the informativeness for relationship (I(R)) and the informativeness for relatedness (I(r)) to measure the amount of information provided by markers in inferring pairwise relationships (R) and relatedness (r), respectively. This offers a quick and efficient way to monitor malaria burden. Dipropylacetic acid did not influence the serum thyroid hormone concentrations, and neither did primidone. The hypercalcemia was caused by vitamin can you drink alcohol when on plavix D intoxication on three separate occasions. Assessment of study quality, however, suggested substantial methodological concerns, particularly in relation to issues of bias and confounding, limiting the robustness of any conclusions around effectiveness.

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We conclude that the Italian HPAI viruses arose from low pathogenicity strains, and that a deletion in the NA stalk followed by the acquisition of additional glycosylation near the receptor binding site of HA1 may be an adaptation of H7 viruses to a new host species i.e. This isolate also possessed the IS1016-bexA partial deletion, which is often associated with increased virulence. Ninety tumours classified as well-differentiated oligodendrogliomas (43 cases) and anaplastic oligodendrogliomas (47 cases) were studied with glial fibrillary acidic protein (GFAP) and bound with different lectins including: peanut agglutinin (PNA), concanavalin A (Con A), wheat germ agglutinin (WGA) and Ricinus communis agglutinin (RCA-1). MBCD treatment (0.5 mM) induced a significant decrease in the cholesterol content of T cells of elderly subjects whereas it was increased in T cells of young subjects. We applied the technique of DNA amplification with the polymerase chain reaction to nine aqueous humor and five vitreous samples from HIV-1-infected patients with clinically diagnosed cytomegalovirus retinitis. This article introduces the use of immersive VR simulators to preventively reduce accidents in the workplace by detecting behavioral patterns that may lead to an increased predisposition to risk exposure. It increases respiration and gluconeogenesis with the same kinetics.

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Thus, experimental evidence suggested that iron mediated its effects via transcriptional activation by PbrA under low iron conditions, while an as-yet-unidentified sigma factor(s) may be required for the PbrA-independent aprA expression and AprA proteolytic activity induced by siderophore and iron. A New Suspending Medium Used for the Intracutaneous Virulence Test of Bacillus Diphtheriae. Some of these surface-active compounds synthesized by marine microorganisms exhibit antimicrobial, anti-adhesive and anti-biofilm activity against a broad spectrum of human pathogens (including multi-drug resistant pathogens), and could be used instead of existing drugs to treat infections caused by them. The best therapy in cases of perforated ulcus corneae is the immediately performed perforating keratoplasty with fresh material as the following up of 7 patients shows. The correlation of the statistics used for selection and the test for association is derived to adjust the two-phase analysis with control of the Type-I error rate. vermiconia, which produce cylindrical and comma-shaped conidia, respectively. The effector caspase is recruited through PYD, whose overexpression induced pyroptosis but only after substantial delay.

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