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Alphapril

Alphapril is a prodrug of an ACE inhibitor used to treat hypertension and congestive heart failure. It is indicated for the management of essential or renovascular hypertension. It is indicated as monotherapy or in combination with other antihypertensive agents, such as thiazide diuretics, for an additive effect.

Other names for this medication:
Acetensil, Alapren, Analept, Anapril, Antiprex, Benalapril, Bidinatec, Carlon, Ciplatec, Clipto, Corodil, Corprilor, Corvo, Denapril, Ditensil, Ditensor, Ednyt, Enaladex, Enalaprilmaleat, Enalaprilum, Enalaprol, Enalek, Enalich, Enalten, Enapril, Enatec, Encardil, Envas, Feliberal, Gadopril, Grifopril, Hipertan, Kalpiren, Konveril, Laprilen, Nacor, Nalapril, Naprilene, Nuril, Prilenap, Renistad, Reniten, Silverit, Supotron, Tensazol, Vapresan, Vasopril

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Also known as: Enalapril

Description

Alphapril (enalapril) is an ACE inhibitor. ACE stands for angiotensin converting enzyme.

Alphapril is used to treat high blood pressure (hypertension) in adults and children who are at least 1 month old.

Alphapril is also used to treat congestive heart failure in adults.

Alphapril is also used to treat a disorder of the ventricles (the lower chambers of the heart that allow blood to flow out of the heart). This disorder can decrease the heart's ability to pump blood to the body.

Dosage

Usual Adult Dose for Hypertension:

Initial dose: 5 mg orally once a day Maintenance dose: 10 to 40 mg orally per day as a single dose or in 2 divided doses Maximum dose: 40 mg orally daily as a single dose or in 2 divided doses In combination with diuretics: Initial dose: 2.5 mg orally once a day If feasible, the diuretic should be discontinued 2 to 3 days prior to initiation of therapy with enalapril. If required, diuretic therapy may be gradually resumed.

Usual Adult Dose for Congestive Heart Failure:

Initial dose: 2.5 mg orally once a day Maintenance dose: 2.5 to 20 mg daily in 2 divided doses Maximum dose: 40 mg orally per day in 2 divided doses Comments: -Treatment is usually combined with diuretics and digitalis. -Doses should be titrated upward, as tolerated, over a period of a few days or weeks.

Usual Adult Dose for Left Ventricular Dysfunction:

Initial dose: 2.5 mg orally twice a day Maintenance dose: 20 mg orally per day in 2 divided doses Comments: -After the initial dose, the patient should be observed for at least 2 hours and until blood pressure has stabilized for at least an additional hour. -If possible, the dose of any concomitant diuretic should be reduced which may diminish the likelihood of hypotension.

Usual Pediatric Dose for Hypertension:

Children 1 month to 17 years: Initial dose: 0.08 mg/kg/day (up to 5 mg) in 1 to 2 divided doses. Adjust dosage based on patient response. Maximum dose: Doses greater than 0.58 mg/kg (40 mg) have not been evaluated in pediatric patients. Comment: -Not recommended in neonates and in pediatric patients with glomerular filtration rate less than 30 mL/min, as no data are available.

Detailed Alphapril dosage information

Overdose

If you overdose Alphapril and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Alphapril overdosage: fainting, dizziness.

Storage

Store at room temperature below 30 degrees C (86 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Alphapril are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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We sought to evaluate our recent experience with surgical treatment of branch pulmonary artery (PA) stenosis both for native and acquired lesions. Langerhans cell histiocytosis (LCH) is a rare immunologic disorder, identified by immature proliferation of histiocytes which may present as systemic or focal lesions. Nuclear phosphatase PPM1G in cellular survival and neural development. Alloxan inhibited subsequent glucose-induced insulin release in a dose-dependent manner at 37 degrees C., with 650 muM alloxan producing 94 per cent inhibition of insulin release. Use of cell image analysis in the detection of cancer from specimens obtained during endoscopic retrograde cholangiopancreatography.

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To investigate several key aspects of phosphatidylinositol transfer protein (PI-TP) function in eukaryotic cells, rat PI-TP was expressed in yeast strains carrying lesions in SEC14, the structural gene for yeast PI-TP (SEC14p), whose activity is essential for Golgi secretory function in vivo. We present a case of blunt traumatic aortic laceration following a motor vehicle crash. The antitumor activity of SPM VIII was superior to that of mitomycin C. The problem is to properly diagnose the disease, manage the patient and deal with the source. Our patient was a 16-year-old female who began with intense headaches suggesting intracranial hyper-tension, as well as with an acute deficit in the left hemisphere. Longitudinal data indicate that, for 15 of 20 indicators, health risk increased and access to health care decreased from the teen and adult years for most US race/ethnic groups.

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C5 nephritic factors drive the biological phenotype of C3 glomerulopathies. At 1-3 days, the tungsten-carrying macrophages were accumulated near the terminal bronchioles whereas they were seen predominantly in the alveolar ducts and sacs in the 7- to 14-day groups of mice. The efficacy and safety of epsilon-aminocaproic acid treatment in patients with cirrhosis and hyperfibrinolysis. To evaluate patients with median nerve damage in the distal forearm treated with type 1 collagen nerve conduits. We reported a case of DIC who was administered FEC90 (5-FU 1,000 mg/body, epirubicin 170 mg/body, cyclophosphamide 1,000 mg/body) for advanced breast cancer. How effective leaders achieve success in critical change initiatives part 4: emergent leadership--an example with doctors. Recent work provides critical insights regarding the underpinnings of the deficits in executive function often observed in those at risk for alcohol dependence and those who develop alcohol use disorders. Hormonal metabolic imbalances in pregnancy and congenital anomalies. Financial status is associated with QOL of Chinese women with recurrent ovarian cancer. Shortterm psychotherapy with hospitalized schizophrenic patients.

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Use of a Remote Eye-Tracker for the Analysis of Gaze during Treadmill Walking and Visual Stimuli Exposition. An analysis of data was performed on 90,900 patients over the age of 18 who were registered as patients with diabetes mellitus in Maccabi Healthcare Service Register which is the second largest health maintenance organization in Israel. The incorporation of conformational averaging of structures from molecular dynamics simulations is discussed, and a hybrid scheme wherein the Hamiltonian matrix from the quantum chemical local-mode approach is combined with fluctuations from empirical schemes is shown to be consistent with experiment. This study suggests that in the setting of implant reconstruction, CPM has a positive correlation with patient satisfaction with their breasts, but not with improvements in other HR-QoL domains. Systemic hemodynamics, vasoactive systems, and plasma volume in patients with severe Budd-Chiari syndrome.

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Strategies for coping with pain presented by adolescents with hematopoietic malignancies. The effect on changes in serum lipids and factors that may affect those changes after administration of icosapentaenoic acid ethyl ester. Recent studies have demonstrated relationships between cytokines and gastric acid secretion. Empathy has been shown to have a very real positive effect on patient outcomes. The British military physicians applied and established West European medical ideas, as well as the principles of preventive medicine, for the first time in the Greek territory and this is a historical example of a successful sanitary campaign based on the experience of military physicians and their collaboration with civilian physicians. Towards the Application of Structure-Property Relationship Modeling in Materials Science: Predicting the Seebeck Coefficient for Ionic Liquid/Redox Couple Systems. Distinctive multisoliton interactions are observed via changing the pump power and adjustment of the waveplates as well as the BP. Patients enrolled in TIMI II were randomly assigned to an invasive (1,681 patients) or a conservative (1,658 patients) management strategy to follow receipt of intravenous recombinant tissue-type plasminogen activator for acute myocardial infarction.

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Indeed, glomerular basement membrane thickening and an altered type IV collagen labeling distribution were only observed after four months of hyperglycemia, suggesting that functional alterations take place early in diabetes prior to any structural modification. However, in the presence of multivessel disease, prognosis after infarction is impaired regardless of diabetes, and the influence of diabetes is less obvious. Combined RNAi targeting human Stat3 and ADAM9 as gene therapy for non-small cell lung cancer. Pregnant rats received control or an ethanol-containing liquid diet starting on the 9th day of gestation and were killed on the 17th day or 21st day, of gestation or allowed to deliver. Calcium phosphate nanoparticle (CaPNP) for dose-sparing of inactivated whole virus pandemic influenza A (H1N1) 2009 vaccine in mice. Other outcome measures addressed cognition, function, global status, side effects, and laboratory data. zofran 4 mg generic name Relaxation exercises, involving the successive tensing and relaxing of the major muscle groups of the body, were performed by four adults with spastic quadraplegia. After partial pancreatectomy without duct occlusion or partial gastrectomy, enzyme treatment should be initiated when exocrine pancreatic insufficiency occurs.

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