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Alpaz (Alprazolam)

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Alpaz is commonly used to treat anxiety and panic disorders. It falls into a category of medications called benzodiazepines. They are known to affect the central nervous system components and produce a calming effect, thus decreasing brain activity.

Other names for this medication:
Aaram, Acalm, Actirax, Alamflu, Alcicalm, Aldip, Alpaz, Alprawin, Alzac, Alzopax, Axizox, Coolam, Cozac, Deproz, Depten, Esteem, Hipose, Jolistar, Notence, Oclam, Onapract, Pecalm, Plxna, Pranol, Prolam, Rescalm, Serex, Silam, Sinzolam, Synozolam, Tenfree, Tenschem, Xycalm, Xylonite, Zenax, Zocam, Zolar, Zoloid, Zolorel, Zopain, Zorest, Zotin

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Arava, Avapro, Detrol, Zantac, Revia, Anxorel, Bunase, Lipirex, Gynapill, Soprodal,

Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alpaz XR. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


If you have been prescribed Alpaz for medical reasons, the best way to avoid a Alpaz overdose is to adhere to prescribed orders—closely monitor your dose and the time at which you take your medication. Track your Alpaz consumption in a notebook or on your phone. If you notice that you are taking a higher dose of the drug, taking the drug more often, or you want to consume more of the drug, talk with your doctor immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alpaz dosage information

Side effects

The most common side effects associated with Alpaz are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not drink alcohol while taking Alpaz XR. This medication can increase the effects of alcohol. Alpaz XR can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Grapefruit and grapefruit juice may interact with Alpaz XR and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.

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Combined Impact of Known Lifestyle Factors on Total and Cause-Specific Mortality among Chinese Men: A Prospective Cohort Study. acnes, increased extracellular TG levels, transporter activity and ABCB1 mRNA expression in DHS. Presentation of one case of prostate adenocarcinoma with a peculiar evolution towards a large cystic formation at the expense of the left prostate lobe, clinically revealed as a picture of poor performance status and impaired consciousness secondary to obstructive renal failure. A deep learning framework for financial time series using stacked autoencoders and long-short term memory. Although survival was short, surgery and involved field radiotherapy yielded a progression-free interval of 9 months. Cisplatin resistance in these clones resulted in part from heightened activation of the IGF-1R/AKT pathway. It was shown for yeast cells of a wild type that the RBE values of pulsed neutrons varied insignificantly with a dose (2.0-1.7) white for continuous neutron irradiation clear RBE dependence on the dose was observed. Amongst the up-regulated miRNAs, miR168a, miR403a, miR162b and miR1515a predictively regulate the expression of AGO1, AGO2, DCL1 and DCL2, respectively, and miR1507a, miR1507c and miR482a putatively regulate the expression of several NBS-LRR family disease resistance genes. Height, weight, and current body mass index (BMI) were positively associated with postmenopausal breast cancer regardless of FH, while these anthropometric factors did not alter risk in premenopausal women. The BHGI collaborated with 12 national and international health organizations, cancer societies and nongovernmental organizations to host two BHGI international summits.

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NaHS (1, 10, and 50 mM) elicited a concentration-response relationship from the majority of recorded neurons, with almost exclusively depolarizing effects following administration. Such a novel theranostic nanoplatform is expected to integrate dual-mode guided imaging with greater therapeutic efficacy and fewer side effects and is very promising for the noninvasive synergistic tumor therapy. The performance of dental or orthopedic implants is closely dependent on surface properties in terms of topography and chemistry. Revision of NP pharmacy law is becoming less necessary as more control of prescribing by guidelines is exercised on nurses and physicians alike. Additionally, the R1antTNF neutralized the TNFR1-mediated bioactivity of wtTNF without influencing its TNFR2-mediated bioactivity and inhibited hepatic injury in an experimental hepatitis model. The purpose of the study reported here was to develop and pilot test a comprehensive battery of assessment instruments for older drivers that would be inexpensive and easy to administer so that it could be used in longitudinal studies. However, results indicate that APCI is better suitable for the ionization of amino acids with polar side chains, whereas ESI proved superior for the ionization of amino acids featuring hydrophobic residues.

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MSeqDR-GBrowse genome browser supports interactive genomic data exploration and visualization with custom tracks relevant to mtDNA variation and mitochondrial disease. Aluminum-catalyzed silicon nanowire growth under low-pressure chemical vapor deposition conditions requires higher reactor pressures than gold-catalyzed growth, but the reasons for this difference are not well understood. In some patients, mild to moderate arthropathy develops despite anatomical glenoid reconstruction. The perceptual consequences of these BM IR interactions are of interest as lead-lag click pairs are often used to study localization and the precedence effect. After surgery, early oral refeeding may be beneficial in the majority of patients undergoing CRS/HIPEC. Children with life-limiting conditions in paediatric intensive care units: a national cohort, data linkage study. Correlations between morphological changes in platelet aggregates and underlying endothelial damage in cerebral microcirculation of mice. Workstation-based peer review can increase completion rates and levels of radiologist acceptance while producing RADPEER scores similar to those previously reported.

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Although impulsive personality traits have been well implicated in substance use disorder (SUD) risk, little work has established how specific impulsive personality traits influence and are influenced by SUD psychotherapy outcomes. All adult immigrants entering Switzerland in 2004 were screened by chest x-ray (CXR). We have developed a testing platform for a novel type of retinal prosthesis. The therapy of chronic nutritional placenta disorders--preliminary results of a double-blind study (proceedings). Butyltin compounds in the Oyster, Saccostrea cucculata, from the west coast of India. The study was carried out with large unilamellar vesicles of three different lipid compositions: 1,2-dimyristoil-sn-glycero-3-phosphocholine (DMPC), 1,2-dimyristoyl-sn-glycero-3-phospho-rac-(1-glycerol) (DMPG), and a 3:1 binary mixture of DMPC/DMPG in a wide range of peptide/lipid ratios. The demonstrated micro-recanalization and sustained growth factor up-regulation at vasectomy sites suggest a possible mechanism for post-vasectomy ejaculate sperm identification. The fractured surface of the alloys with severe hydrogen charging exhibited dimple patterns similar to those in the alloys from patients. XVII Congress of the SENPE (Spanish Society of Parenteral and Enteral Nutrition). Prescribing spectacles: reasons for failure of spectacle lens acceptance.

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Discriminative Block-Diagonal Representation Learning for Image Recognition. The noise power spectrum was abnormal, containing two components of different time course. Loss of tumour coverage was the predominant effect observed with tumour motion in this study. The in vitro behaviour of both series of compounds may be regarded as similar. Taxonomy and hospital dissemination of the Mallophaga species Trabeculus rudow, 1866. TGB concentrations were notably lower in the retina than in the brain. Here, the authors show that observers have striking misconceptions about what the motion of projectiles should look like from various perspectives and that they estimate when the physical apex of a fly ball occurs to be far later than actual, irrespective of baseball experience. differs from its congeners mainly in possessing seven sparsely ciliated cirral rows that are conspicuously shortened posteriorly and three transverse cirri aligned in a row.

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Non-trauma-associated additional findings in whole-body CT examinations in patients with multiple trauma. The specific issues concern the definition of the Rorschach, research about the test stimuli, and the expansion of information concerning the interpretive usefulness of some structural variables that are poorly conceptualized or for which interpretation may be overly generalized. Mechanical disruption of lyophilized material in high-salt medium and treatment with proteinase K, followed by sedimentation of the lysate into saturated CsC1 solution yielded pure, highly polymerized DNA. Low skeletal muscle mass is a predictive factor for chemotherapy dose-limiting toxicity in patients with locally advanced head and neck cancer. Epigenetic alterations occur in an unsystematic manner or as part of the aberrant transcriptional machinery, which promotes selective advantage to the tumor cells. Patchy nest distributions resulted in a highly right-skewed frequency distribution of local under-yearling densities (among 25 m sampling sections), as sample sections adjacent to the nest sites had relatively high densities. Xanthomatous bilary cirrhosis secondary to carcinoma of the extrahepatic bile ducts. Guidelines for diagnosis and treatment of chronic rhinosinusitis (2012, Kunming).

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Targeting FOXM1 Improves Cytotoxicity of Paclitaxel and Cisplatinum in Platinum-Resistant Ovarian Cancer. Group 1 received oral anticoagulant (nicoumalone) treatment, stabilised over five days before surgery and continuing into the second postoperative week. After the induction of orthodontic tooth movement activation of macrophages, osteoclasts and odontoclasts was demonstrable, all of them showing a clear-cut positive reaction to ED1. The benefits of physical activity during cancer treatment are similar to those experienced after treatment. Four of seven cases of erythema multiforme were due to M pneumoniae infection. We used a WHOQOL-BREF questionnaire, based on the existing WHO recommendation and its meaningful metric characteristics. Anatomy of the greater omentum was studied in 129 human cadavers with a special regard to its size, shape and type of blood supply. The role of (18)fluorodeoxyglucose positron emission tomography (PET) is limited for detection of primary hepatocellular carcinoma (HCC) due to low contrast to the tumor, and normal hepatocytes (background). A quantitative immunostaining method for the measurement of UDP-galactose:lactosylceramide galactosyltransferase for the synthesis of globotriaosylceramide in rabbit small intestine and HeLa cells.

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An increase of 86Rb uptake was found in the heart, lungs, and adrenals 15 minutes after administration of polysaccharide-protein complex. The currently available scientific data are summarized with regard to cancer development and detection, implant rupture and gel migration, and autoimmune disorders. We investigated the combination of selective serotonin reuptake inhibitors (SSRIs) with the beta-adrenoceptor/serotonin 1A (5-HT(1A)) antagonist pindolol, based on the concept that 5-HT(1A) receptor blockade would eliminate the need for desensitization of presynaptic 5-HT(1A) receptors and therefore hasten the onset of action and improve the efficacy of SSRIs. Attenuation of endothelium-dependent relaxing factor (EDRF) release may contribute to adverse sequelae commonly seen after reperfusion of an acutely ischemic extremity. The aim of this study was to identify markers for the differential diagnosis of non-small-cell carcinomas. Toll-Like Receptor 4 Deficiency Causes Reduced Exploratory Behavior in Mice Under Approach-Avoidance Conflict.

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All urgent and elective anesthetic procedures performed by anesthesiologists were included. Obtaining the desired response with these strategies is unpredictable because many of these signals have both tolerogenic and immunogenic roles. DC-mediated cytotoxic T lymphocyte (CTL) activation and antitumor immunity were significantly enhanced by Egr2-KD, and impaired by Egr2 overexpression in antigen-pulsed DC vaccines. This appears to conflict with a reported recent decline, unless asthma prevalence peaked in the 1990s. The efficacy of epicillin in enteric fever (a comparative study with that of chloramphenicol). Here we report single-unit ganglion cell recordings from 5- to 6-day-old zebrafish larvae.

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Clinical evaluation of the Makari test in urological malignancies. In this study, the authors estimated inpatient costs, LOS, and in-hospital mortality for patients with subarachnoid hemorrhage (SAH), intracerebral hemorrhage (ICH), ischemic cerebral infarction (ICI), and TIA who were treated in community hospitals. How then are the relevant cellular signals for the induction and expression of long-term synaptic changes conveyed between the nucleus and remote synaptic terminals?. We sought to determine the differential effects of ambient environmental temperature challenge and UCP1 activation in relation to cardiovascular disease progression. Prime/boost vaccination strategies for HIV/SIV vaccine development have been used since the early 1990s and have become an established method for eliciting cell and antibody mediated immunity. Further structural insights into the binding of complement factor H by complement what happens if you drink alcohol while taking ambien regulator-acquiring surface protein 1 (CspA) of Borrelia burgdorferi. niger HT4 strain, which has the ability to degrade these compounds for obtaining a potent bioactive molecule such as ellagic acid. It is hypothesized that this increased transposon mobilization leads to genomic instability and thus sterility, although no causal link has been established between transposon upregulation and genome instability.

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Measured variable path analyses were used to determine the predicted can you drink alcohol on lamisil pathways linking self-efficacy, social support and PPC to diabetes self-care and glycemic control. Because treatment does not stop the infection from spreading, the bull was culled to prevent the risk of infection of the national herd. Fibers from the anteromedial nucleus are distributed largely in cortical layers V and VI of the anterior and posterior limbic regions. Surgical techniques of cranial vault expansion for increases in intracranial pressure in older children. At the instance of the rheogram the mode of function is described. Evaluation of Muscle Performance in Mice by Treadmill Exhaustion Test and Whole-limb Grip Strength Assay. Mechanical injury alters volume activated ion channels in cortical astrocytes. Mosaic genome structure of the barley powdery mildew pathogen and conservation of transcriptional programs in divergent hosts. Pharmacokinetic parameters were analyzed based on trough concentrations and 24-hour pharmacokinetic profiles. In the liver, the exposure to Cd resulted in an increase of GSH level and the activity of rhodanese, while the activity of 3-mercaptopyruvate sulfurtransferase and cystathionase decreased.

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This review discusses the advantages and limitations of employing 1H-MRS as an investigative tool in the diagnosis of ALS. five-session treatment of dental phobia: a randomized controlled study. The inhibitory effects of DL on epithelial cell GM-CSF secretion and on eosinophil survival induced by epithelial cell secretions, suggest that this H(1) antagonist may regulate eosinophil inflammation in upper airways. An initial search of MEDLINE (via PubMed) and CINAHL was undertaken, followed by a second search for published and unpublished studies since 1975 in major healthcare-related electronic databases. Therapeutic effectiveness of ultrasonics and lidase phonophoresis in various forms of scleroderma. Loss of Pten Disrupts the Thymic Epithelium and Alters Thymic Function. We found that binding sites strongly reduced the levels of expression at early times postinfection and that this effect was partially overcome after the onset of viral DNA replication. It is concluded that the ASQ can contribute to the understanding of cognitive processes during treatment of agoraphobia. Long-term effects of methylphenidate on neural networks associated with executive attention in children with ADHD: results from a longitudinal functional MRI study. The main toxic effects were myelosuppression, alopecia, paresthesia, asthenia, myalgia, and hyporeflexia.

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Inflammatory bowel disease: epidemiology, pathogenesis, and therapeutic opportunities. Inhibition of neutral endopeptidase in dogs with pacing induced heart failure protected endogenous atrial natriuretic peptide from degradation and stimulated sustained natriuresis, presumably via a tubular mechanism. Staphylococcus xylosus used as starter culture in sausages decreases the level of volatile organic compounds arising from lipid oxidation and so contributes to the aroma by avoiding rancidity. Deviation of the typical AAA substrate-threading pore prevents fatal protein degradation in yeast Cdc48. We have produced ttk protein ectopically in blastoderm-stage embryos transformed with a heat shock-ttk construct. The full characterization of submucosal lesions may be difficult with optical colonoscopy alone, and endoscopic biopsy is often nondiagnostic. This will help us to design and synthesize the polymer fluorescence material. Our PACS vendor is working on concurrent image databases that would be capable of nearly immediate switchover and recovery.

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