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Alnacob (Gabapentin)
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Alnacob

Alnacob is an antiepileptic and analgesic for nerve pain. Scientists don't know exactly how it works, but it has a similar structure to gamma-aminobutyric acid (GABA), a chemical in the brain that calms nerves.

Other names for this medication:
Carecobal, Comago, Divinerv, Freenerve, Gabacent, Gabalept, Gabarone, Gabil, Gabion, Gabpam, Gapin, Gentin, Juvigen, Mecoslib, Mecotop, Mecova, Mecovon, Methybex, Methylife, Micknerve, Mycolin, Nerverich, Nerwin, Neupent, Neurocob, Neurogab, Nexcob, Nicomin, Ntomec, Nuromark, Nuropentin, Nurotin, Progaba, Rejunate, Wintin, Zepentine, Zincobal, Zintigo

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Also known as: Gabapentin

Description

Alnacob (gabapentin) is an anti-epileptic drug, also called an anticonvulsant. It affects chemicals and nerves in the body that are involved in the cause of seizures and some types of pain.

Alnacob is used in adults to treat neuropathic pain (nerve pain) caused by herpes virus or shingles (herpes zoster).

Alnacob is also used to treat seizures in adults and children who are at least 3 years old.

Use only the brand and form of gabapentin your doctor has prescribed. Check your medicine each time you get a refill to make sure you receive the correct form.

Dosage

Usual Adult Dose for Epilepsy:

Initial dose: 300 mg orally on day one, 300 mg orally 2 times day on day two, then 300 mg orally 3 times a day on day three Maintenance dose: 300 to 600 mg orally 3 times a day Maximum dose: 3600 mg orally daily (in 3 divided doses) -Maximum time between doses in the 3 times a day schedule should not exceed 12 hours Comment: -May be taken with or without food. -Half-tablets not used within 28 days of breaking the scored tablet should be discarded. Use: Adjunctive therapy in the treatment of partial onset seizures, with and without secondary generalization

Usual Adult Dose for Postherpetic Neuralgia:

-Initial dose: 300 mg orally on day one, 300 mg orally 2 times day on day two, then 300 mg orally 3 times a day on day three -Titrate up as needed for pain relief -Maximum dose: 1800 mg per day (600 mg orally 3 times a day) COMMENT: -May be taken with or without food. -Half-tablets not used within 28 days of breaking the scored tablet should be discarded.

Usual Pediatric Dose for Epilepsy:

Less than 3 years: Not recommended Greater than or equal to 3 and less than 12 years: Starting Dose: Ranges from 10 to 15 mg/kg/day in 3 divided doses Effective Dose: Reached by upward titration over a period of approximately 3 days; the effective dose in patients 5 years of age and older is 25 to 35 mg/kg/day in divided doses (3 times a day). The effective dose in pediatric patients ages 3 and 4 years is 40 mg/kg/day and given in divided doses (3 times a day). Gabapentin may be administered as capsule, or tablet, or using combinations of these formulations. Dosages up to 50 mg/kg/day have been well tolerated in a long term clinical study. The maximum time interval between doses should not exceed 12 hours. Greater than 12 years: -Initial dose: 300 mg orally on day one, 300 mg orally 2 times a day on day two, then 300 mg orally 3 times a day on day three -Maintenance dose: 900 to 1800 mg orally in 3 divided doses; the dose may be increased up to 1800 mg/day. Dosages up to 2400 mg/day have been well tolerated in long term clinical studies. Doses of 3600 mg/day have also been administered to a small number of patients for a relatively short duration, and have been well tolerated. The maximum time between doses in the three times a day schedule should not exceed 12 hours. Use: Adjunctive therapy in the treatment of partial onset seizures, with and without secondary generalization in patients 3 years of age and older

Detailed Alnacob dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Alnacob are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Alnacob if you are allergic to gabapentin.

To make sure Alnacob is safe for you, tell your doctor if you have ever had:

breathing problems or lung disease, such as chronic obstructive pulmonary disease (COPD); kidney disease (or if you are on dialysis); diabetes; depression, a mood disorder, or suicidal thoughts or actions; a drug addiction; a seizure (unless you take Alnacob to treat seizures); liver disease; heart disease; or (for patients with RLS) if you are a day sleeper or work a night shift.

Some people have thoughts about suicide while taking this medicine. Children taking Alnacob may have behavior changes. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Seizure control is very important during pregnancy, and having a seizure could harm both mother and baby. Do not start or stop taking Alnacob for seizures without your doctor's advice, and tell your doctor right away if you become pregnant.

If you are pregnant, your name may be listed on a pregnancy registry to track the effects of gabapentin on the baby.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

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Live-cell imaging of exocyst links its spatiotemporal dynamics to various stages of vesicle fusion. Arsenic trioxide (As2O3) is a promising anticancer agent for solid tumors. Analysis of X prilosec dose in children -ray photoelectron spectroscopy indicated the molecular state nitrogen was incorporated into TiO2 lattice leading to the observable shift of the absorption edge to longer wavelength region with higher absorption intensity. Increases in serum concentrations of C-reactive protein (CRP) and soluble adhesion molecules sE-selectin and sICAM-1 are regarded as risk factors of atherosclerosis now. Several outbreaks have made the news in 2016 : Ebola has come at an end, Zika is booming and a resurgence of yellow fever takes place in Africa. These results raise the possibility that ET-1, part of whose production is triggered by infectious postgraft complications, might play a role in the development of BOS through its potential effects on airway remodeling. 50 patients with obstruction of the FPA underwent CTA and digital subtraction angiography examinations of the lower limbs. Proliferation and micronucleus production was monitored every 2 h in the 4- and 8-cell stages.

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