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Alfresh (Alprazolam)

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Alfresh is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alfresh, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alfresh is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Actirax, Alfix, Allam, Alprac, Alpracon, Alpron, Alprotame, Alwe, Alzoact, Alzoax, Alzonex, Alzopax, Alzotime, Anlzium, Anxyl, Avizolem, Axizox, Benzax, Berest, Cqlam, Dipra, Ecsit, Endolam, Faxtin, Fluxin, Fultop, Hipose, Oclam, Pralam, Prosanti, Rescalm, Restyl, Selam, Sinaday, Somnarest, Somnia, Tenschem, Tensyl, Trika, Ziety, Zopam, Zopax, Zopic, Zopral

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Diamox, Protonix, Ambien, Wellbutrin, Cipro, Elavil, Imitrex, Dulcolax, Periactin, Isogest, Diligan, Albengel, Depsol, Neurocin, Azicalm, Trampar, Ancer, Clatic, Veniz,

Also known as: Alprazolam


Alfresh (alprazolam) is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). It is thought that alprazolam works by enhancing the activity of certain neurotransmitters in the brain.

Alfresh is used to treat anxiety disorders and anxiety caused by depression.

Alfresh is also used to treat panic disorders with or without a fear of places and situations that might cause panic, helplessness, or embarrassment (agoraphobia).

It is dangerous to purchase Alfresh on the Internet or outside the United States. The sale and distribution of medicines outside the U.S. does not comply with safe-use regulations of the Food and Drug Administration (FDA). These medications may contain dangerous ingredients, or may not be distributed by a licensed pharmacy.


Usual Adult Dose for Anxiety:

Immediate-release tablets: 0.25 to 0.5 mg orally administered 3 times a day -Maximum dose: 4 mg/day

Usual Adult Dose for Panic Disorder:

Immediate-release tablets: 0.5 mg orally administered 3 times a day -Maximum dose: 10 mg/day Extended-release tablets: -Initial dose: 0.5 to 1 mg orally once a day -Maintenance dose: 3 to 6 mg orally per day, preferably in the morning -Maximum dose: 10 mg/day Comments: -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage. -The daily dosage may be decreased by no more than 0.5 mg every 3 days; however, some patients may require an even slower dosage reduction. -The dose of extended-release tablets may be increased at intervals of 3 to 4 days in increments of no more than 1 mg per day. -The times of administration should be distributed as evenly as possible throughout the waking hours.

Usual Geriatric Dose for Anxiety:

Elderly or debilitated patients: Immediate-release tablets: 0.25 mg orally administered 2 or 3 times a day.

Usual Geriatric Dose for Panic Disorder:

Elderly or debilitated patients: Immediate-release tablets: -Initial dose: 0.25 mg orally administered 2 or 3 times a day Extended-release tablets: -Initial dose: 0.5 mg orally once a day Comments: -If side effects develop, the dose may be lowered. -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage.

Detailed Alfresh dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alfresh dosage information

Side effects

The most common side effects associated with Alfresh are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not use Alfresh if you are pregnant. It could harm the unborn baby.

Do not use this medication if you are allergic to Alfresh or to other benzodiazepines, such as chlordiazepoxide (Librium), clorazepate (Tranxene), diazepam (Valium), lorazepam (Ativan), or oxazepam (Serax).

Before you take Alfresh, tell your doctor if you have asthma or other breathing problems, glaucoma, kidney or liver disease, a history of alcoholism, or a history of depression, suicidal thoughts, or addiction to drugs or alcohol.

Do not drink alcohol while taking Alfresh. This medication can increase the effects of alcohol.

Alfresh may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it.

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Assortative mating, or the tendency for individuals with similar phenotypes to mate more frequently than expected by chance, has been reported for a variety of complex traits, including many neuropsychiatric disorders. A better understanding of the cost of birth setting is needed to inform policy makers and service providers. Early nifurtimox-induced biochemical and ultrastructural alterations in rat heart. The ninth international congress of the Croatian Society of Nuclear Medicine - Rovinj, May 04-07, 2017. Those individuals who met the MetS criteria had increased cardiovascular disease. Coronary artery disease continues to be one of the leading causes of death and disability around the globe, challenging the efficacy of currently applied schemes to predict the risk for future coronary events. Such evaluation was possible due to the combined responses of a photosensor based on titanium dioxide in suspension, of an enzymatic biosensor based on superoxide dismutase (SOD), of a specific conductivity sensor and of an enzymatic biosensor based on glucose oxidase. A baseline comprehensive health survey including door-to-door survey for non-respondents to the comprehensive survey, was performed in 1986, and repeated at follow-up five years later.

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ALS diagnostic criteria of El Escorial Revisited: do they meet the needs of clinicians as well as researchers?. To analyze the symptomatic factors of rheumatoid arthritis (RA), and to explore the correlations between these factors and the efficacy of TCM herbal and western medicinal therapies. Under the ALF, a significant dosing time dependency was demonstrated for the toxicity of MTX with a longer survival time for the middark dosing and a shorter one for the midlight dosing. This is due to the fact that the vein, being disconnected from its natural braces, is compressed by the inguinal ligament. The Use of PARP Inhibitors in Cancer Therapy: Use as Adjuvant with Chemotherapy or Radiotherapy, Use as a Single Agent in Susceptible Patients, and Techniques Used to Identify Susceptible Patients. The object of this study was to determine the in vitro biochemical and cellular inhibitory profile of cabozantinib against RET, and in vivo antitumor efficacy using a xenograft model of MTC. A correlation between shortened life span and UV-sensitivity in some strains of Saccharomyces cerevisiae. Especially, it is unknown whether the basal ganglia (BG)-forebrain loop which implements song learning in juveniles by driving vocal exploration participates in seasonal plasticity.

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This study used musculoskeletal modeling techniques to analyze rectus femoris musculo-tendon (MT) length and lengthening velocity during stiff knee gait in 35 children with diplegic cerebral palsy (CP). Study of modifiable risk factors for asthma exacerbations: virus infection and allergen exposure increase the risk of asthma hospital admissions in children. Mycobacterium tuberculosis infection may protect against allergy in a tuberculosis endemic area. The results of this study indicate that while a large proportion of the participants with brain injuries were integrated in traditional areas of service delivery such as medical services, housing and social activity, their disability-related needs were not being identified and supported adequately in the areas of spirituality and productive activity. All subclones showed a reduced growth rate with respect to parental cell lines but each had a different resistance mechanism. Most evidence indicates that oxidized low density lipoprotein (ox-LDL) is responsible for initiating these functional abnormalities, and that it affects the endothelium rather than vascular smooth muscle cells. It was found that a DNA segment as large as 17 kb cloned in pBR322 can be readily transferred to the B. Local granulocyte-macrophage colony-stimulating factor improves incisional wound healing in adriamycin-treated rats. After 10 weeks of this treatment the patient reported absence of joint/muscle symptoms and of joint noise.(ABSTRACT TRUNCATED AT 250 WORDS).

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Potentiation by means of the transformation in barbiturate derivatives of the local anesthetic activity by means of certain basic aryl-ureas. Selection of floating-point or fixed-point for adaptive noise canceller in somatosensory evoked potential measurement. Viral genomes maintained extrachromosomally in hamster polyomavirus-induced lymphomas display a cell-specific replication in vitro. We study an XXX open spin chain with variable number of sites, where the variability is introduced only at the boundaries. Online social networking offers the potential to break through the glass ceiling imposed by at least the second of these, potentially enabling us to maintain much larger social networks. The analysis was adjusted for 1-year change in BMI and demographic and health-related factors, as well as reports by proxies, and death occurring during the first 2 years after the interview.

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The 25F9-positive macrophage-stimulated tumor cell proliferation and inhibited migration completely. Content, in vivo release, and bioactivity of fetal pulmonary immunoreactive adrenocorticotropin. Comparison of TCLL with chitinases and other chitin binding CLPs shows that TCLL has substitution of some chitin binding site residues and more open binding cleft due to major differences in the loop region. Coincidence of dorsal defect on a multipartite patella constitutes a rare cause of anterior knee pain in the first decades of life. Using general lineal models, incongruence was found to be the variable with stronger relations with psychopathology even when controlling for diagnosis. Persistent protein misfolding initiates apoptotic cascades that are now known to play fundamental roles in the pathogenesis of multiple human diseases including diabetes, atherosclerosis and neurodegenerative diseases. Here, we describe the biology of MHC-II and MHC-II variations that affect immune responses. A clinical application of laser direction in anastomosis for inferior canalicular laceration. Mycobacterium tuberculosis is extraordinarily sensitive to killing by a vitamin C-induced Fenton reaction.

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Time trends in absolute and relative socioeconomic inequalities in leisure time physical inactivity in northern Sweden. Neuropeptide Y and corticotropin-releasing hormone are involved in the regulation of various physiological functions including the expression of anxiety and fear. Under anaerobic conditions it can utilize nitrate as a terminal electron acceptor, whereby dinitrogen is released. Performance on the Wada naming and comprehension subtests was better in the nonsurgical hemisphere than in the surgical hemisphere in the RATL group, but there was no difference between the nonsurgical and the surgical hemisphere naming and comprehension performance in the LATL group. Temporal changes in combat casualties from afghanistan by nationality: 2006-2010. Differences across population groups were investigated, with a focus on 15- to 34-year-olds, the highest risk age group. High-Temperature Stable Anatase Titanium Oxide Nanofibers for Lithium-Ion Battery Anodes.

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In particular, the analysis of purines, pyrimidines, nucleosides and related compounds in blood and serum for the diagnosis and treatment of inherited diseases and cancer is described. The Nuclear and Mitochondrial Genomes of the Facultatively Eusocial Orchid Bee Euglossa dilemma. However, because these results are derived from secondary prevention trials, we cannot be sure if these benefits apply to all diabetic subjects or only to those who already have IHD. Here we describe the induction, by phosphorus stress, of genes from the Trichodesmium erythraeum IMS101 genome that are predicted to encode proteins associated with the high-affinity transport and hydrolysis of phosphonate compounds by a carbon-phosphorus lyase pathway. With recovery of his mutism, CBF increased in the right thalamus, bilateral medial frontal lobes and left temporal lobe. High sensitivity and specificity concerning the absence of inferior labial and lingual frenula has been reported in Ehlers-Danlos syndrome, but the diagnostic value of this finding has been contested. Efforts to increase calcium intake in Hispanics also need to account for ethnic differences. Lentivirus-based gene transfer has the potential to efficiently deliver DNA-based therapies into non-dividing epithelial cells of the airway for the treatment of lung diseases such as cystic fibrosis. However, the full field topography of the largest peak within the first 130 msec does not have a predictable latency or topography in different subjects. The statistical properties that are observed in genomic sequences and are reproduced by the proposed model are: (i) deviations from randomness at different length scales, measured by suitable algorithms, (ii) a special form of size distribution (power law distribution) characterising different levels of genome organisation in the non-coding, and (iii) extensive resemblance in the alternation of coding and non-coding regions at several length scales (self-similarity) in long genomic sequences of higher eukaryotes.

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The relationship of serum mitochondrial creatine kinase and rotavirus gastroenteritis in pediatric patients. There is a lack of practical decision support tools useful for a rapid assessment of the potential of ecosystem services when retrofitting permeable pavements in urban areas that either feature existing trees or should be planted with trees in the near future. Many genes responsible for the bioactivation of endogenous estrogen to reactive quinonoid metabolites, including cytochrome P450 (CYP) 1A1, 1A2, and 1B1, are well-known target genes of the aryl hydrocarbon receptor agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Conditioned social preference, but not place preference, produced by intranasal oxytocin in female mice. The pharmacologic activities of two thrombin inhibitors (D-MePhe-Pro-Arg-H, recombinant-hirudin) were compared in two animal models. The results are in agreement with the international level, but follow-up treatment requires attention in Finland.

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Seroprevalence of antibodies against Toxoplasma gondii, rubella virus, hepatitis B virus, HIV and Treponema pallidum in foreign pregnant women in Elche (Spain). Thus using liposomes of phosphatidylserine to target membrane microdomains is a feasible mechanism for modulating rhinovirus-induced signaling, and potentially a prototypic new therapy for viral-mediated inflammation. The mechanism of inactivation was delineated using activity assays as well as turbimetric and spectroscopic methods. Banding studies of chromosomal abnormalities in patients with acute lymphocytic leukemia. Storage at 10 degrees C appears to be slightly superior to storage at 22 degrees C. Data from two new studies do not support this functional similarity hypothesis, but these data do support the KAE by showing test-retest reliability. The transition between these SLs is shown to induce a change in magnetic scattering between isotropic MR discovered in the area inside the A-phase (the A-phase core) and anisotropic MR found on the border of the A-phase.

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Genetic transmission of status dysraphicus from a clinical viewpoint (proceedings). We describe a novel polymerase chain reaction (PCR) based method using clone-specific immunoglobulin heavy-chain gene sequences as tumor markers. Interspecific competition between bacteria shapes community dynamics, causing evolutionary changes that affect life history traits. The higher sensitivity of this phased array permits use of imaging pulse sequences for which the head coil is inadequate. Myeloid-related protein 8/14 (MRP8/14) forms stable heterodimers and is the major calcium prilosec dose kids -binding protein secreted by activated granulocytes and monocytes. The DeltamntH, DeltafeoB, and DeltafeoB DeltamntH strains were as virulent as the wild type in either of the infection models.

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Stacking cross-sectional intravascular images permits three-dimensional rendering of endovascular implants, yet introduces between-frame uncertainties that limit characterization of device placement and the hemodynamic microenvironment. Monoclonality in reactive lymphadenopathy: gene rearrangement and multiparameter analysis. a detailed and unique list of codes, referred to Ateco91 ISTAT classification with exclusion of the State Railways and the public administration sectors, has been developed. In this study, we investigated the effects of LPS on the expression of TMEM16A in LA795 cells and mouse lung tissue and the potential mechanism. Atosiban is a synthetic oxytocin antagonist that is currently undergoing dose-ranging clinical trials. In breast cancer, IL-19 expression is correlated with increased mitotic figures, advanced tumor stage, higher metastasis, and poor survival. Participants were asked to complete a number of clinical measures.

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In this study, we used stable isotope labeled IgG2b monoclonal antibody, iGlycoMab, as an internal standard to reduce potential for errors and to reduce variabililty due to sample digestion, derivatization, and fluctuation of nanoESI efficiency in the LC-MS analysis of permethylated N-glycans released from model glycoproteins, human blood serum, and breast cancer cell line. Characteristics and inhibition by flavonoids of 20alpha-hydroxysteroid dehydrogenase activity in mouse tissues. To evaluate long-term results of laparoscopic treatment of boys with impalpable testes and sensitivity of preoperative ultrasound. Subtraction hybridization studies, used to identify genes involved in the control of enterocyte proliferation and/or differentiation, allowed detection of a clone shown to have homologies with rat, chicken, and human acidic ribosomal phosphoprotein P1. This descriptive case series, comprising 22 patients with spontaneous perforation of bile duct over a period of 24 months.

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Surgery after midfacial trauma is aimed at restoring both form and function. Continuous venovenous haemofiltration using a citrate buffered substitution fluid. Magnesium dilates both the epicardial and resistance coronary arteries in humans. The effectiveness of varicella vaccination in children in Germany: a case-control study. The p21 activated kinases (PAKs) are a family of serine/threonine kinases that are downstream effectors of small GTPase Cdc42 and Rac. However, the increased application of WSNs also introduces new security challenges, especially related to privacy, connectivity, and security management, repeatedly causing unpredicted expenditures. Activation patterns of the thumb muscles during stable and unstable pinch tasks. Tumoral secretion markers: something more than clinical indicators. It has been used for decades, implementing diagnostic and therapeutic procedures in the subglottis and cervical and thoracic trachea.

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Force-frequency relations in the isolated papillary muscles of rats and guinea-pigs were compared using isometric force measurement technique. Intracellular calcium chelator, BAPTA-AM, prevents cocaine-induced ventricular fibrillation. Clinical and pathological analysis of 128 cases of tonsillar tumor. Management of a hemorrhage of vulvo-vaginal (non-obstetrical) origin. Beneficial effect of amino acid supplementation, especially cysteine, on body nitrogen economy in septic rats. External advice from an expert team with combined surgeons and infectious disease physicians may help to reduce antibiotic consumption in a cost-effective way. Lentivirus-mediated short hairpin RNA (shRNA) against MGP gene expression (MGP-KD) in C6-2 cells or lentivirus-mediated overexpression of MGP transcripts in C6-1 cells resulted in the morphological alteration of the two cell lines. Two patients had transient aphasia, 2 experienced worsened hemiplegia on opposite sides of their bodies, and 2 had mild hemiplegia and language function disturbance. Clonality was noted in five of the eight centers with strains meeting the criteria for molecular typing. Interaction between epidemiology and laboratory sciences in the study of birth defects: design of birth defects risk factor surveillance in metropolitan Atlanta.

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Locally pedicled muscle flap-plasty in traumatology of the lower leg. Several million metric tons of mining wastes, called stamp sands, were generated in the Upper Peninsula of Michigan during extensive copper (Cu) mining activities in the past. Endometrial laser intrauterine thermotherapy for the treatment of dysfunctional uterine bleeding: the first British experience. The antibody titers were measured by both dot blot analysis and ELISA using Keyhole limpets hemocyanin coupled CPT peptides. The patient had a successful outcome after resection of the aneurysm with tracheal repair and esophageal resection. The use of a combination of several procedures is essential for obtaining an accurate diagnosis of cervical involvement in cases of uterine corpus carcinoma. Plectin rodless isoform expression and its detection in mouse brain. With respect to assay validity, a plasma standard could be suitable for assaying concentrated preparations of von Willebrand factor. Our data supports that can i take zyrtec and cold medicine at the same time the Ross procedure is the AVR of choice in children.

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