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Alfacalcirol (Calcitriol)
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Alfacalcirol

Alfacalcirol is an active metabolite of vitamin D that is used to treat hyperparathyroidism and is also used in dialysis patients to combat hypocalcemia. Alfacalcirol is a biologically active calcitrophic hormone with anti-osteoporotic, immunomodulatory, anticarcinogenic, antipsoriatic, antioxidant, and mood-modulatory activities.

Other names for this medication:
Alcee, Alfacal, Alfacip, Alfarich, Alphadol, Arcium, Biocitral, Bonestat, Bonetuf, Calbec, Calcikind, Calcirol, Calcitriol, Calcor, Calfa, Calgel, Calosto, Calotec, Calsonic, Calsure, Caltin, Caltive, Calvical, Calzem, Carcal, Cholical, Citroj, Coecoral, Devita, Dmcal, Koncal, Kurecal, Laretol, Lctrol, Minroset, Netxod, Novadee, Nutribone, Osteobel, Ostonex, Politrol, Refirm, Riecal, Rockbon, Roical, Rolsical, Romical, Sorvate, Trolec, Vezocal

Similar Products:
Vantin, Starlix, Rulide, Danocrine, Aristocort, Famvir, Lioresal, Arava, Feldene, Aygestin, Jutaclin, Nebinorm, Megapress, Sinact, Brolax, Deptune, Sulotrim,

Also known as: Calcitriol

Description

Vitamins are compounds that you must have for growth and health. They are needed in small amounts only and are available in the foods that you eat. Vitamin D is necessary for strong bones and teeth.

Lack of vitamin D may lead to a condition called rickets, especially in children, in which bones and teeth are weak. In adults it may cause a condition called osteomalacia, in which calcium is lost from bones so that they become weak. Your doctor may treat these problems by prescribing vitamin D for you. Vitamin D is also sometimes used to treat other diseases in which calcium is not used properly by the body.

Ergocalciferol is the form of vitamin D used in vitamin supplements.

Some conditions may increase your need for vitamin D. These include:

Alcoholism Intestine diseases Kidney disease Liver disease Overactivity of the parathyroid glands with kidney failure Pancreas disease Surgical removal of stomach

In addition, individuals and breast-fed infants who lack exposure to sunlight, as well as dark-skinned individuals, may be more likely to have a vitamin D deficiency. Increased need for vitamin D should be determined by your health care professional.

Alfacalcidol, calcifediol, calcitriol, and dihydrotachysterol are forms of vitamin D used to treat hypocalcemia (not enough calcium in the blood). Alfacalcidol, calcifediol, and calcitriol are also used to treat certain types of bone disease that may occur with kidney disease in patients who are undergoing kidney dialysis.

Claims that vitamin D is effective for treatment of arthritis and prevention of nearsightedness or nerve problems have not been proven. Some psoriasis patients may benefit from vitamin D supplements; however, controlled studies have not been performed.

Injectable vitamin D is given by or under the supervision of a health care professional. Some strengths of ergocalciferol and all strengths of alfacalcidol, calcifediol, calcitriol, and dihydrotachysterol are available only with your doctor's prescription. Other strengths of ergocalciferol are available without a prescription. However, it may be a good idea to check with your health care professional before taking vitamin D on your own. Taking large amounts over long periods may cause serious unwanted effects.

Dosage

Generic Alfacalcirol is available in capsules (0.25 mcg) and liquid form. Capsules must be swallowed whole. Do not crush or chew them. If you are prescribed the liquid form, use as directed. Follow dosing instructions closely. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. If you want to achieve most effective results do not stop taking Generic Alfacalcirol suddenly.

Overdose

If you overdose Generic Alfacalcirol and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Side effects

The most common side effects associated with Alfacalcirol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Generic Alfacalcirol if you are allergic to Generic Alfacalcirol components. Do not take Generic Alfacalcirol if you are pregnant, planning to become pregnant, or are breast-feeding. It is not known if this medication appears in breast milk. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Be careful with Generic Alfacalcirol if you have heart disease, kidney disease or kidney stones, coronary artery disease (hardening of the arteries). Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. It can be dangerous to stop Generic Alfacalcirol taking suddenly.

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Grazing can be conceptualized on the spectrum of disordered eating behavior, and appears associated with loss of control over eating. Further, coadministration of vitamin A did not inhibit in vivo antitumour activity of methotrexate. The bioreductive drug SR 4233 (a benzotriazine which exhibits preferential cell killing under hypoxic conditions) was combined with photodynamic therapy to exploit the induced hypoxia. The effects of primary, patent Plasmodium berghei infection in Sprague-Dawley rats during pregnancy upon the course of infection and the humoral antibody response to malaria in their offspring were examined. RT-PCR and Western blotting were used respectively to detect the level of EGFL7 mRNA and protein form 33 fresh laryngeal carcinoma tissues and matched para-neoplastic non-tumor tissues. To compare the microbiological yield of corneal ulcer cultures established by direct inoculation of culture media vs indirect inoculation by means of transport medium (Amies without charcoal). Changes in measures following administration of agents were reciprocal in nature.

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This study evaluated the effect of a new hydrolizate from poultry feathers on growth kinetics and aminopeptidase activities of eight bifidobacteria compared with common peptones. These observations suggest that brain amyloid deposition results in low CSF Abeta(42), and that amyloid imaging and CSF Abeta(42) may potentially serve as antecedent biomarkers of (preclinical) AD. Dhanwantram kashaya (DK), a synthetic herbal formulation, is widely used in Ayurvedic medicine as a growth stimulant in children and for nerve regeneration. DLBCL in the spine is rare and minimal information has been published in the literature regarding this subject. Classification and statistical tests conducted on a set of radiographies with their own ground truth corroborate the advantage of the proposed method. Manifestation of allergic disease depends on genetic predisposition, diet and commensal microbiota. When lung primordia were grafted alone, type II pneumocytes did not differentiate. When the text- and pictorial-based question sections were analyzed separately, both groups significantly improved their mean text-based score, whereas only the composite group increased their mean pictorial-based questions score. Fusion of sagittal suture in adult skulls otherwise normal is a new anatomical variant having limited clinical significance and has not been reported so far as far as known to the author. Both metacyclic and bloodstream VSG ESs are transcribed by the multifunctional T.

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Deletion of immunoregulatory cells during Ficoll-sodium metrizoate isolation of human peripheral blood lymphocytes. The experimental use of discussion groups among the patients of a general hospital. The results obtained from this multicenter study demonstrate that the administration of SonoVue to patients with ischemic cerebrovascular disease who undergo TCCS examination of cerebral vessels improves the visualization of intracranial arteries, providing a dose-dependent contrast enhancement and a clinically useful duration of signal enhancement related to the dose. We propose that serpin dimers initiate and propagate polymerisation by having one exposed loop with an optimal conformation as a beta-strand donor and a readily opened beta-sheet as an acceptor. The influence of psychological and other factors on reaction time in the bull. Comparative performance of biomarkers of alcohol consumption in a population sample of working-aged men in Russia: the Izhevsk Family Study. Data analyses demonstrate the reliability of the DMI for minorities, with tendencies toward the internalizing polarity of the composite (object relations) measure. The metabolism of neoplastic tissues: the effect of 2:4-dinitrophenol on glycolysis and ATP-dephosphorvlation of ascites tumour cells and homogenates.

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Thioredoxin-1 stimulates cell growth and is an inhibitor of apoptosis. The aim of this review is to summarize the relationship between mechanobiology and adipogenesis. Providers caring for Latino infants with acute respiratory illness ordered more antibiotics and diagnostic testing for this group, particularly compared with African Americans, even though the 2 groups had similar disease severity and socioeconomic disparities. Ceftriaxone-associated urolithiasis and post-renal acute renal failure (PARF) in adults is exceedingly rare and perhaps underappreciated. Adjusting for other factors, an earlier enrollment date was the sole demographic characteristic associated with an increased risk of delayed ART initiation.

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Despite increasing evidence underscoring callous-unemotional (CU) traits as a marker for youth with CD prone to especially poor outcomes, researchers have yet to explore whether CU traits confer additional risk of early sexual intercourse, unprotected sex, and pregnancy. Enzyme relationships in the action of organophosphorus insecticides. Biocidal activity of chicken defensin-9 against microbial pathogens. A simple techinque for carrying out the immunofluorescence procedure is described that eliminates the problem of drying of antiserum and reduces cost per test. Heparin-releasable midkine may originate from endothelial cells. The material comprised 28 patients (14 pairs) who had all been operated on for glaucoma in one eye by trabeculectomy. The Hybrid Multi-Scale Vector Quantization algorithm developed at Texas Technological University and other automated systems were used to improve digitized cervical images.

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Three-dimensional time-resolved fluorescence imaging by multifocal multiphoton microscopy for a photosensitizer study in living cells. The average time until ambulation after LNU and ONU was 2.2 days (range 1-3) and 4.0 days (range 3-5), respectively. Increased serum 3-nitrotyrosine is associated with impaired driving ability. The greater effect obtained by inoculating the vaccine in two doses could thus be misleading and we suggest the adoption of a test in which a single dose is given. Using a novel method of marking pre-NACT tumor margins with indigenous silver wire markers, this prospective pilot study attempted to assess the feasibility of safe BCS in LABC patients by performing excision wide of the marked pre-NACT margins. However, considerable room remains to optimise management, particularly with development of systems of care to facilitate prompt referral and delivery of angiography in these high-risk individuals. This tumor should be considered in the differential diagnosis of round to short spindle cell tumors arising in the lung. We demonstrated the clinical characteristics of each member of a family from Oki Island in western Japan, whose members have familial amyotrophic lateral sclerosis (FALS) with a 2-base pair (bp) deletion at codon 126 of Cu/Zn superoxide dismutase (SOD1) gene. Beef (Bos taurus) production forms a large component of the Irish agricultural industry and accounts for more than one quarter of agricultural economic output.

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Biological significance of agmatine, an endogenous ligand at imidazoline binding sites. SEIs are products of strand exchange between one DSB end and its homolog. Possible implications for the clinical use of the H2 breath test. A biocompatible injectable thermo-responsive hydrogel, hyaluronic acid-g-chitosan-g-poly (N-isopropylacrylamide) (HA-CPN), was used as a biomimetic organic gel matrix while embedded biphasic calcium phosphate (BCP) ceramic micoparticles were used to replace mineralized matrix. Haplotype analysis was uninformative for the fourth mutation (Arg403Gln). The primary outcome is to compare the time it takes for a baby being treated with TO versus OM for NAS to be medically cleared for discharge. Cofilin knockdown significantly suppressed rod formation but did not prevent actin aggregation. Inhibition of IL-6 production by IL-4 in monocytes was associated with decreased nuclear NF-kappa B levels. The open-field test is a commonly used apparatus in many behavioral studies. This study suggests that hyperthyroidism affects bone mineralization especially during the early postmenopausal period, and the effect is mainly at the cortical bone.

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moseri juveniles and adults, when searching for ascidians use chemical cues to avoid hosts occupied by conspecifics. Here, we address this issue by examining the determinants of maize diversity in a local region of high cultural and biological richness in Southern Mexico. A second patient with transplanted kidney and immunosuppression therapy has been given care to with total cystectomy and supravesical derivation of the urine by a ileal conduit of a solid cancer or urinary bladder. The present paper reports on two methods for extraction of the protein antigen from Treponema Reiter and shows the chemical and immunochemical characteristics of the extracts. Application of cinder gel-beads/reeds combination strategy for bioremediation of pyrene- and indeno(1,2,3-cd)pyrene-contaminated estuarine wetlands. Engineering functional epithelium for regenerative medicine and in vitro organ models: a review.

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T2A has a characteristic amino acid composition rich in the basic amino acid, lysine. Assuming that the escape rate from a cluster depends only on the cluster size, the dynamics of the model is directly mapped to the mathematically well-studied zero-range process. Immunization with vectors without a secretory signal sequence before the scFv resulted in markedly higher bactericidal activity relative to those with such a sequence. In the murine tumor model, administration of rHuIFN-alpha A/D at 4 hours after light onset and rMuIFN-gamma at 16 hours after light onset may produce maximum antitumor activity. Our method is highly efficient, resulting in precise, markerless mutations. Society-research-diagnosis: have classification problems in psychiatry been overcome at the beginning of the new millennium?. Cytological and isoenzyme analysis of the Bucay and Quevedo cytotypes of the Onchocerciasis vector Simulium exiguum (Diptera: Simuliidae) in Ecuador. To assess the interobserver agreement in a semi-automated quantification approach of MR-renal perfusion and filtration parameters with a two-compartment model analysis. We introduce a general scheme for calculating from first principles both the transverse-optical and longitudinal-optical infrared absorption spectra at surfaces or interfaces.

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These data suggest that structural similarities between melatonin and auxin do not result in similar postnatal effects on reproductive and non-reproductive organ development on a long photoperiod and further suggest that melatonin and auxin do not operate through a common physiological mechanism. We analyzed monospecific and cross-reactive recognition by diverse TCRs of an immunodominant HVH-1 glycoprotein B epitope (HSV-8p) bound to two closely related MHC class I molecules, H-2K(b) and H-2K(bm8). Subjective data on skin thickness, edema and sensory impairment were obtained using a visual analogue scale (VAS). In an unrelated observation, there was a correlation between the incubation period of a strain of scrapie in F2 generation mice and their coat color, i.e., the average incubation period of yellow-brown mice was significantly less than those of either black or white mice. The blood of former malaria suffers, in order to avoid the risks of transfusion malaria, should be used only after seroimmunological studies have demonstrated the absence of anti-malaria antibodies. Thus locomotor adaptation is not dependent on a change in action during learning but instead can be driven entirely by an unexpressed internal recalibration of the desired movement. The polysaccharide (SGP) was chemically modified to obtain its sulfated derivatives (S-SGP) using the method of chlorosulfonic acid/pyridine (CSA/Pyr). A novel mutation in the mitochondrial 16S rRNA gene in a patient with MELAS syndrome, diabetes mellitus, hyperthyroidism and cardiomyopathy. With respect to the patients with lumbar pain, the asymptomatic group proved to have wider foramina from L3 to L5 and wider sagittal diameters in S1. This investigation compared glutaraldehyde (GTA)-sensitive and -resistant strains of Mycobacterium chelonae and examined the effects of pretreatment of GTA-sensitive and -resistant strains of Myco.

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Ultrastructural aspects of cell surface carbohydrates--a review. Together, these results demonstrate for the first time a functional ANLS in a human stem cell-derived co-culture. Malignant peripheral nerve sheath tumour of the heart in a horse. In this review, we highlight the regulation of posttranscriptional events in EMT by RNA-binding proteins (RBPs). Nevertheless, both approaches represent a decisive step forward compared to conventional optimizations.

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Various variables should be considered in a natural ensemble to comprehensively assess the determinants of protein evolutionary rate. pregnancy and lactation) on the susceptibility to gastrointestinal nematodes was studied in the Dodoma and Kigoma strains of small East African goats in Morogoro. Simulation in obstetrics and maternal-fetal medicine is an educational tool that can be employed to address local and national learning objectives for residents and fellows. HBO1, but not SRC-2, expression was reduced in protonix dosage pregnancy testes of patients with AIS compared to normal testes. We report a patient who developed a type B aortic dissection and ruptured his aneurysmal sac 1 year after endovascular abdominal aortic aneurysm repair (EVAR), despite standard follow-up.

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Physical and chemical properties of the crystalline rabbit muscle enzyme. We included a total of 487 patients who sustained civilian gunshot wounds to the spine and were provided care at Rancho Los Amigos Rehabilitation Center from 2001 to 2014. A compact tri-modal system was successfully built and evaluated for planar mode operation. Large clinical studies have generally shown a significant proportion of seizures to be triggered by emotions. Human rights: a critical framework for the response to HIV/AIDS. The author comments on the main aspects of the evolution of methods of diagnosis and treatment in pediatric urology during the past 20 years. It is suggested that L-ASA or part of its molecule may bind to and inhibit cyclo-oxygenase in the blood vessel wall in a manner similar to the acetylation of platelt cyclo-oxygenase. No history of migraine or ischemic event were documented in any.

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The genetic characterization of HIV-1 breakthrough infections in vaccine and placebo recipients offers new ways to assess vaccine efficacy trials. This and other forms of service integration may represent a valuable intervention to enhance PMTCT and maternal health. Robust principal component analysis (RPCA) is an efficient method in the identification of differentially expressed genes. Complications were due to the persistent presence how long to wait to drink alcohol after taking diflucan of haemangiomas within the liver, where an impressive collection of platelets and a superinfection were observed. In the last decade, new data regarding macrophages and dendritic cells and the high therapeutic success of anti-tumor necrosis factor alpha biologics led to the assumption that antigen-presenting cells are important not only in the induction of psoriasis but also in its maintenance.

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Hormones, growth factors and metabolites control the function is theophylline an antibiotic of PP1 holoenzymes mainly by modulating the interaction of the subunits. Our results indicate that the common Mediterranean mutations are frequent in the Azeri Turkish FMF patients but with some differences in the frequency of individual mutations. To evaluate the efficacy of vaginal misoprostol in therapeutic termination of second trimester pregnancy with a live fetus. In this work, evidence for the switch from children to adult associated microbial profile between 1 and 2 years of age was provided, suggestively driven by Bifidobacterium breve. CalQuo 2 analyzes the calcium response in the Fourier-domain, allowing the number of user-defined filtering parameters to be reduced to one and a greater diversity of calcium responses to be recognized, compared to CalQuo that directly interprets the calcium intensity signal. These results suggest that GIP may have previously undescribed actions. Wolff-Parkinson-White Syndrome with Ventricular Hypertrophy in a Brazilian Family. Patients were divided into two groups: open cholecystectomy in 16 patients and percutaneous transhepatic gall bladder drainage in 17 patients.

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