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Aldactone (Spironolactone)
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Aldactone

Aldactone is a prescription medicine used to treat the symptoms of high blood pressure (hypertension), low potassium levels (hypokalemia) and heart failure. Aldactone may be used alone or with other medications. Aldactone belongs to a class of drugs called Aldosterone Antagonists, Selective, Diuretics, Potassium-Sparing.

Other names for this medication:
Aldostix, Amifru, Aquamide, Dyamide, Dytor, Fruselac, Frusis, Lactone, Lasilactone, Metolactone, Spilactone, Spiromide, Spironolactone, Spirotic, Torlactone, Tormax, Torsid, Zator

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Also known as: Spironolactone

Description

Aldactone (spironolactone) is a potassium-sparing diuretic (water pill) that prevents your body from absorbing too much salt and keeps your potassium levels from getting too low.

Aldactone is used to treat heart failure, high blood pressure (hypertension), or hypokalemia (low potassium levels in the blood).

Aldactone also treats fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or a kidney disorder called nephrotic syndrome.

Aldactone is also used to diagnose or treat a condition in which you have too much aldosterone in your body. Aldosterone is a hormone produced by your adrenal glands to help regulate the salt and water balance in your body.

Dosage

Usual Adult Dose of Aldactone for Edema:

25 to 200 mg orally per day in single or divided doses

Usual Adult Dose of Aldactone for Hypertension:

Initial dose: 50 to 100 mg orally per day in single or divided doses

Usual Adult Dose for Congestive Heart Failure:

Initial dose: 25 mg orally once a day assuming serum potassium is less than or equal to 5 mEq/L and serum creatinine is less than or equal to 2.5 mg/dL

Usual Adult Dose for Primary Hyperaldosteronism:

Diagnostic dose:

Usual Adult Dose for Hypokalemia:

25 to 100 mg orally per day

Detailed Aldactone dosage information

Overdose

If you overdose Generic Aldactone and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Aldactone overdosage: diarrhea, vomiting, nausea, red skin rash, loss of energy, slow heartbeat, weakness in legs, feeling drowsy, confusion.

Storage

Store below 25 degrees C (77 degrees F). Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Aldactone are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Generic Aldactone if you are allergic to Generic Aldactone components. Do not take Generic Aldactone if you're pregnant or you plan to have a baby, or you are a nursing mother. Generic Aldactone can harm your baby. Do not take Generic Aldactone if you are taking potassium-sparing diuretics (such as Aldactazide, amiloride (Moduretic, Midamor)), triamterene (such as Maxzide, Dyazide, Dyrenium)). Be careful using Generic Aldactone if you take inhibitors (enalapril (such as Vasotec), fosinopril (such as Monopril), captopril (such as Capoten), benazepril (such as Lotensin), lisinopril (such as Zestril, Prinivil), quinapril (such as Accupril), moexipril (such as Univasc), ramipril (such as Altace), trandolapril (such as Mavik)); oral steroids (dexamethasone (such as Decadron, Dexone), prednisone (such as Deltasone), methylprednisolone (such as Medrol)); aspirin and other nonsteroidal anti-inflammatory medicines (naproxen (such as Aleve, Naprosyn), ibuprofen (such as Advil, Motrin), indomethacin (such as Indocin)); diuretics; barbiturates, phenobarbital; digoxin (such as Digitek, Lanoxicaps, Lanoxin)); high blood pressure medicines, lithium (such as Lithobid, Eskalith); perindopril (such as Aceon).It can be dangerous to use Aldactone if you suffer from or have a history of liver disease, kidney disease, potassium high levels in your blood, problems with urination. Be careful with this drug if you are going to have a surgery. Avoid food with high level of salt. Avoid dehydration. Avoid medicines which cause lightheadedness. You should be careful when you are driving or operating machinery. Do not stop taking Generic Aldactone suddenly.

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Blood group frequencies of immigrant and indigenous populations from South East England. Having a human interface improves communication among physicians, patients, nurses, and families. A comparison between the frequency of Hb S heterozygotes in blood donors, outpatients, and inpatients of a general hospital carried out at the Maputo Central Hospital, Mozambique, where Plasmodium falciparum malaria is endemic, showed a statistically significant lower percentage of Hb S heterozygotes in the inpatient group. Effects of age on the quality of care provided to older patients with acute myocardial infarction. The present work aimed to study the impact of amino acids on S6K1 activity in quail muscle (QM7) myoblasts. The intravenous data were obtained from a previous study of the pharmacokinetics of serum digoxin and its inotropic response (derived from systolic intervals) in 12 normal male volunteers.

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Analysis of the tet repressor-operator interactions using the uracil-DNA glycosylase footprinting system. A series of anatomic dissections defined the likely site of injury to be at the junction of the vocal process of the arytenoid cartilage and the membranous true vocal cord approximately 6 to 10 mm below the level of the cord. At the onset of XCI, deleting Xite downregulates Tsix in cis and skews XCI ratios, suggesting that Xite promotes Tsix persistence on the active X. It usually occurs as a result of catheter migration, omental or small bowel entrapment, or fibrin clots. Analysis of health plan disenrollment by Medicaid clients indicated that the most common reason was loss of Medicaid eligibility. Epileptic drop attacks in partial epilepsy: clinical features, evolution, and prognosis. We examined the reversibility of the changes in (ultra)structure and gap junctions. The technical details required in performing these procedures and the developmental anatomy of this and other major venous anomalies are discussed. The effects of the presence of metal irises on guided-mode propagation through a symmetrical three-layer slab waveguide are examined by using the integral equation method. However, titanium 6-4 alloy was found to be especially susceptible to abrasive wear by particles of acrylic cement.

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Examining rates of comorbid personality disorder in broad-based community samples of bipolar spectrum patients would further clarify the linkage between these sets of disorders. Therefore, the present findings may contribute to the recognition of intratumoral hemodynamics. The procedure is based on horizontal ultrathin-layer multi-zonal (HUME) electrophoresis of PCR fragments in polyacrylamide gels followed by silver staining. A comparative study of surgical suture materials and closure techniques. However, although nNOS-immunoreactive terminals were frequently evident in the NTS, none were vagal afferent in origin. To identify phosphotyrosine-containing proteins essential for maintaining the transformed state, we studied the tyrosine phosphorylation profile of temperature-sensitive mutant of Rous sarcoma virus, tsNY68, infected cells (68N7). Depressed individuals and controls were scanned while they attempted to voluntarily down-regulate sad feelings. We report here a case of this syndrome associated with membranoproliferative glomerulonephritis. Moreover, by means of FTA-ABS-IgM and 19 S-IgM-FTA-ABS-test valuable diagnostic additional informations (early diagnosis of the infection, L.

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To study the expression of heme oxygenase-1 (HO-1) in dental pulp tissue and to find out the relationship of distribution and function of HO-1. We subsequently combined our first and second data sets in an attempt to enhance the evidence for linkages in a larger sample size. Multiple wells allowed experimental and control observations on the same vascular segments. Besides rulide tablet 150 mg several other advantages, aortic valve replacement with a pulmonary autograft may result in improved hemodynamic characteristics compared to other valve replacement procedures. Co-localization of G protein pathway signalling molecules probably contribute to both spatial and temporal regulation of signal transduction. The authors analyzed data from the Commonwealth Fund Survey of Parents With Young Children, a national sample of 2,017 parents with children younger than 3.

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Morphologic and mucin histochemical analysis of transitional zones in advanced ulcerated colorectal carcinomas: potential prognostic indicators. Dose-dependent influence of commercial garlic (Allium sativum) on rats fed cholesterol-containing diet. T2 relaxation times were measured by using a spin echo sequence. To assess the efficacy and tolerance of fluconazole (150 mg oral dose, once a week) in the prevention of recurrent oropharyngeal candidiasis in patients with moderate to severe human immunodeficiency virus (HIV) infection. Common anions present in natural waters and humic acid were evaluated for their effects on NO3(-) hydrogenation over a bimetallic supported catalyst (Pd-Cu/gamma-Al2O3). The purpose of this study was to evaluate changes in the left ventricular performance using Doppler index of myocardial performance (sum of isovolumic contractile and relaxation times divided by left ventricular ejection time) and left ventricular remodelling after PTSMA for HOCM. Clustergrammer enables producing interactive web based visualizations for the analysis of diverse biological data. Understanding the pathogenesis of periodontitis: a century of discovery. No direct binding of monoglucosylated ribonuclease B or monoglucosylated glycans to ERp57 could be detected, but we show that ERp57 interacts directly with calnexin.

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