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Agoxin (Digoxin)

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Agoxin is a medication used to treat various heart conditions. Most frequently it is used for atrial fibrillation, atrial flutter, and heart failure. Agoxin is taken by mouth or by injection into a vein. Agoxin is only available on prescription.

Other names for this medication:
Agoxin, Cardiacin, Cardiogoxin, Digacin, Digibind, Digitek, Digobal, Digohan, Digoregen, Digosin, Digossina, Digoxen, Digoxin, Digoxine, Digoxinum, Eudigox, Fargoxin, Halfdigoxin, Lanadicor, Lanibos, Lanicor, Lenoxin, Purgoxin, Sigmaxin, Vidaxil

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Also known as: Digoxin


Digoxin injection is given in combination with a diuretic (water pill) and an angiotensin-converting enzyme (ACE) inhibitor to treat heart failure in adults and children. It is also used to treat adults with atrial fibrillation (a heart rhythm problem).

Digoxin belongs to the class of medicines called cardiac glycosides. It is used to improve the strength and efficiency of the heart, or to control the rate and rhythm of the heartbeat. This leads to better blood circulation and reduced swelling of the hands and ankles in patients with heart problems.

This medicine is to be given only by or under the direct supervision of a doctor.


This section provides information on the proper use of a number of products that contain digoxin. It may not be specific to Agoxin Pediatric. Please read with care.

To keep your heart working properly, take this medicine exactly as directed even though you may feel well. Do not take more of it than your doctor ordered and do not miss any doses. Take the medicine at the same time each day. This medicine works best when there is a constant amount in the blood.

When you are taking this medicine, it is very important that you get the exact amount of medicine that you need. The dose of digoxin will be different for different patients. Your doctor will determine the proper dose of digoxin for you. Follow your doctor's orders or the directions on the label.

Measure the oral solution correctly using the marked measuring dropper that comes with the package or an oral syringe. Do not use teaspoons and tablespoons that are used for serving and eating food. They do not measure exact amounts.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For heart failure or atrial fibrillation: For oral dosage form (solution): Adults, teenagers, and children 10 years of age and older—Dose is based on age, body weight, and medical condition and must be determined by your doctor. At first, the dose is usually 10 to 15 micrograms (mcg) per kilogram (kg) of body weight. Your doctor may adjust your dose as needed. However, the maintenance dose is usually 3 to 4.5 mcg per kg of body weight per day. Children 5 to 10 years of age—Dose is based on age, body weight, and medical condition and must be determined by your doctor. At first, the dose is usually 20 to 35 micrograms (mcg) per kilogram (kg) of body weight. Your doctor may adjust your dose as needed. However, the maintenance dose is usually 5.6 to 11.3 mcg per kg of body weight per day. Children 2 to 5 years of age—Dose is based on age, body weight, and medical condition and must be determined by your doctor. At first, the dose is usually 30 to 45 micrograms (mcg) per kilogram (kg) of body weight. Your doctor may adjust your dose as needed. However, the maintenance dose is usually 9.4 to 13.1 mcg per kg of body weight per day. Infants 1 month to 24 months of age—Dose is based on age, body weight, and medical condition and must be determined by your doctor. At first, the dose is usually 35 to 60 micrograms (mcg) per kilogram (kg) of body weight. Your doctor may adjust your dose as needed. However, the maintenance dose is usually 11.3 to 18.8 mcg per kg of body weight per day. Full-term babies—Dose is based on age, body weight, and medical condition and must be determined by your doctor. At first, the dose is usually 25 to 35 micrograms (mcg) per kilogram (kg) of body weight. Your doctor may adjust your dose as needed. However, the maintenance dose is usually 7.5 to 11.3 mcg per kg of body weight per day. Premature babies—Dose is based on age, body weight, and medical condition and must be determined by your doctor. At first, the dose is usually 20 to 30 micrograms (mcg) per kilogram (kg) of body weight. Your doctor may adjust your dose as needed. However, the maintenance dose is usually 4.7 to 7.8 mcg per kg of body weight per day. For oral dosage form (tablets): Adults—Your doctor will give your first few doses intravenously (rapid digitalization) and then, you'll be switched to oral tablets for maintenance therapy. A maintenance dose of 0.125 to 0.5 milligram (mg) once a day will be given depending on your body weight and medical condition. Teenagers and children older than 10 years of age—Dose is based on body weight and must be determined by your doctor. Children younger than 10 years of age—Use and dose must be determined by your doctor.


If you overdose Agoxin and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Agoxin overdosage: confusion, irregular heartbeats, nausea, seizures, vomiting, extremely fast or slow heartbeats, hallucinations, tiredness, problems with vision, diarrhea, lack of appetite.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Agoxin dosage information

Side effects

The most common side effects associated with Agoxin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies on the relationship of age to the effects of digoxin have not been performed in the pediatric population. However, infants are more likely to be very sensitive to the effects of digoxin which may require an individual dose for infants receiving digoxin.

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Experimental determination of muscular work capacity for repetitive static work in a predetermined work-rest rhythm. We recently established that in two chicken DT40 mutants (1/2delta110kb and delta57kb), which lack, respectively, one allele of the gene cluster of 110 kb carrying six H1 genes, plus 33 core histone genes, and two copies each of four of the six H1 genes included in an approximately 57 kb segment of the cluster, expression of the remaining H1 genes is increased, resulting in constant steady-state levels of total H1 mRNAs. Enzymuria and beta 2-microglobulinuria are sensitive markers of injury to renal tubular cells. This method was successfully utilized to validate a newly developed preclinical smoking model in mice. We describe studies of a human leukocyte antigen, termed is bystolic a safe blood pressure medication Leu-13, that is defined by a mouse monoclonal antibody that reacts with T and B lymphocytes. A recently developed co-culture system provides evidence that a local feedback loop may exist between sympathetic neurons and adipose tissue. Ovariectomy was performed on 12 rabbits, which composed the osteoporotic model group. In five patients, recurrence was detected 9 to 23 months after diagnosis of the initial lesion. Risk factors for enterococcal urinary tract infection and colonization in a rehabilitation facility.

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B16-F10 melanoma cells are highly metastatic to the lungs and we showed that lymphocytes treated with the regulatory B16-RNA reduce significantly the number of metastatic nodules. Computed tomography is thus highly sensitive in detecting irreversibly damaged ischemic brain tissue. Conservative myomectomy in the complex treatment of patients with uterine myoma. Oxitropium bromide improves exercise performance in patients with COPD. The aim of the study was to compare the efficacy and safety of the topical scabicides: permethrin, crotamiton and sulfur ointment. To evaluate the plasminogen activator system in women with polycystic ovary syndrome (PCOS). Quantitative localised proton MR spectroscopy of white matter revealed marked reduction of N-acetylaspartate, creatine, and choline with normal values for myo-inositol, consistent with axonal loss and astrocytic proliferation. Immunological effects of zinc deficiency in sickle cell anemia (SCA).

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A single nucleotide substitution at the rib2 locus of the yeast mitochondrial gene for 21S rRNA confers resistance to erythromycin and cold-sensitive ribosome assembly. Lemierre disease in the pediatric intensive care unit, clinical course, and the use of high-frequency oscillatory ventilation. We examined the physico-chemical properties and the functions of beta-actinin by using a beta-actinin preparation having the same properties as those reported by Maruyama et al. A strategy for the management of pressure ulcers in nursing homes. However, the results suggest that factors other than radical formation are of importance in explaining the tissue damage upon reperfusion. This is the first of a series of articles on probability calculation, consisting of a simple introduction to the definitions of probability. Due to proximity of the enzymes to one another several advantages in the analyses were achieved. Measurement of flow in perfused organs, using microsphere techniques. Just after parturition, the litter size and the gestation period were recorded and the mandibular size of the newborn offspring was measured by use of an image analyzing system.

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British cross sectional population survey of people aged 65 and over. During the multiple dosing period average steady-state plasma drug concentrations were 0.149 mg/ml and 0.145 mg/ml for the 300 mg twice a day and 200 mg three times a day regimens, respectively. The inferred functions of hypA and hypB suggest a mechanism for coordinating apical growth, subapical cell arrest, and mitosis in A. The vaccine F-strain, represented by cultures can u take cough medicine with zyrtec designated F-K810 and F-F2F10 was clearly differentiated from other strains of M. A double-blind comparative study of ketanserin with atenolol in essential hypertension. A major source of such variation is the nonuniformity of the B1 magnetic field of the radiofrequency coil. Biochemical status of muscle was evaluated with P-31 MRS by determining concentrations of inorganic phosphate (Pi), phosphocreatine (PCr), ATP, and phosphodiesters during rest and exercise.

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