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Afeditab (Nifedipine)

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Afeditab is a dihydropyridine calcium channel blocker. Afeditab is used to: treat high blood pressure (hypertension), prevent chronic stable angina (chest pain). Afeditab was the first calcium channel blocker to be shown to significantly reduce the development of new overt heart failure in patients with coronary artery disease. Excellent blood-pressure control in recent clinical trials has been shown to result in significant protection against stroke. Afeditab works by opening up blood vessels in the body to lower blood pressure and improve the supply of blood and oxygen to the heart. Calcium channel blockers do not change the amount of calcium in your blood or bones.

Other names for this medication:
Addos, Calcianta, Calcigard, Cardicon, Conducil, Cordafen, Cordipin, Corotrend, Depin, Farmalat, Fenamon, Herlat, Hexadilat, Lemar, Milfadin, Nefelid, Nifebene, Nifecard, Nifecor, Nifed, Nifediac, Nifedipin, Nifedipress, Nifelat, Nifensar, Nifeslow, Nifestad, Nifical, Niften, Nipin, Nipress, Noviken, Nyefax, Sidalat, Xepalat, Zenusin

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Arava, Azulfidine, Symmetrel, Clomid, Zyrtec, Loxitane, Prilosec, Praten, Momnom, Prestole, Cupan, Klarithran, Varizil, Mastor, Biliff,

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Afeditab PA 20. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Afeditab and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Nifedipine dosage information

Side effects

The most common side effects associated with Afeditab are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of nifedipine in the pediatric population. Safety and efficacy have not been established.

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Expression of dystrophin-associated glycoproteins during human fetal muscle development: a preliminary immunocytochemical study. In the group of patients studied retrospectively, the two patients with atypical adenoma had an aneuploid DNA pattern. Insufflation with CO2 carries the risk of hypercapnia, gas embolism and pneumothorax. Rhodopsin and opsin form structural dimers that are organized in paracrystalline arrays. A new therapeutic approach in trophic defects of the lower extremities. An analysis of the operation records for the years from 1910 to 1980 shows a considerable increase in the indication for surgical treatment. Legal issues relating to the obligation to provide quality services were discussed as were ethical issues relating to where the responsibility for providing such service lies. All patients experienced a reduction in breathiness of voice that was rated as a significant improvement by the patient and surgeon.

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Cerebrovascular mortality seems highest in moderately prosperous countries where the diet is largely vegetarian, but includes proteinaceous plants and oil seeds beside carbohydrates, tending to decrease in the most prosperous countries where a considerable proportion of the dietary intake is of animal origin. Antinociception induced by alpha-2-adrenoceptor agonists, with special emphasis on medetomidine studies. The effect of obstructions and thermals in laminar-flow systems. The results confirmed those of an earlier meta-analysis in demonstrating the utility of aphasia treatments, generally considered, for bringing about desirable clinical outcomes. A retrospective review of the mammograms of 1845 histopathologically proven breast cancer cases revealed five NEDBC. We report a case of cervical anterior spinal artery syndrome (ASAS). Videourodynamic study, urethral pressure profilometry (UPP), and abdominal leak point pressure study were performed at baseline and after PFMT. Preparation and characterization of monoclonal antibodies against equine chondrocytes, osteoblasts and osteocytes.

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Effect of docosahexaenoic acid-rich fish oil supplementation on human leukocyte function. Forensic analysis of bicomponent fibers using infrared chemical imaging. Health status and income: the impact of poverty on child health. Cytogenetic analysis of spleen cells obtained from a splenomegalic male mouse neonatally inoculated with cell-free extract indicated that the tumor cells urispas price tablet had a male karyotype with 42 chromosomes as compared to 37 chromosomes and a female karyotype in original BCL1 cells, thus excluding the possibility of tumor propagation by transplantation of intact BCL1 cells. Demonstration of activity is the major goal of Phase II studies. Production and immunohistochemical characterization of monoclonal antibodies against ovarian antigen of the common tree shrew (Tupaia glis). Molecular characterization of the p53 protein has shown that its conformational flexibility and intrinsic thermodynamic instability provide a foundation from which its conformation can be quickly post-translationally modified.

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Screening of 37 matched sarcoid derived DNA samples confirmed the presence of BPV in 34 diseased donkeys. The cDNA encoding hTPO receptor (c-Mpl) was cloned from human erythroleukemia (HEL) cells by reverse transcription-polymerase chain reaction (RT-PCR) and linked to the human cytomegalovirus promoter in pcDNA3 to yield expression plasmid phTR. Disinfection of human enteric viruses in water by copper and silver in combination with low levels of chlorine. The microvascular cast as a three-dimensional tissue skeleton: visualization of rapid morphological changes in tissues of the rat uterus. Terminal cells mutant for myospheroid, the major Drosophila beta-integrin, or doubly mutant for multiple edematous wings and inflated alpha-integrins, also show the tendrils phenotype, and localization of myospheroid beta-integrin protein is disrupted in tendrils mutant terminal cells. Assembly and cloning of coding sequences for neurotrophic factors directly from genomic DNA using polymerase chain reaction and uracil DNA glycosylase. Histopathological examination is needed, firstly before urethroplasty to exclude already existing malignant changes of the urethral mucosa and secondly whenever suspicion is raised after surgery. Types of neurons, synaptic tramadol medication dogs connections and chemical characteristics of cells immunoreactive for calbindin-D28K, parvalbumin and calretinin in the neocortex. The enzymes, produced during growth of the microorganisms, reach the protein-coated surface by diffusion in the agar.

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Abnormal gallium-67 citrate imaging in tuberculosis appearing like sarcoidosis. The etiology is usually congenital for those tumors arising within the apex, but acquired for lesions secondarily invading the apex. Determination of correction factors of 3H-beta-self-absorption for quantitative evaluation of grain number in autoradiographic studies. The implants made a solid connection with no oscillation or dislodgment from the external pressure used for distraction. In addition, we found a higher expression of CRH type-1 and 2 receptors mRNAs in preparations of adrenal cortices as compared to pheochromocytomas, a 6 albendazole oral suspension ip zentel dosage -fold increase in preparations of clinically unapparent adrenocortical adenomas, and a 10- to 60-fold increase in cortisol-producing adrenal adenomas. Protective effect of tetramethylpyrazine on ischemic neuronal damage in the gerbil hippocampus.

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