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Admadol (Tramadol)

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Admadol is a centrally-acting opioid agonist and SNRI (serotonin/norepinephrine reuptake inhibitor) used for the management of moderate to severe pain in adults. Admadol is a centrally acting synthetic opioid analgesic and SNRI (serotonin/norepinephrine reuptake-inhibitor) that is structurally related to codeine and morphine.

Other names for this medication:
Accupain, Acupain, Adamon, Bludol, Bolodol, Cadol, Contramal, Damadol, Damol, Dolomed, Dolriz, Jpdol, Leedol, Nopidol, Novadol, Opidol, Opiran, Oshdol, Postadol, Rybix, Ryzolt, Sayodol, Tacil, Tandam, Traceta, Traiz, Tramacon, Tramagesic, Tramak, Tramospas, Tramot, Trapain, Trasic, Trugesic, Trydol, Tryme, Ultrax

Similar Products:
Fasigyn, Skelaxin, Tricor, Daklinza, Deltasone, Aygestin, Estrace, Rocaltrol, Luvox, Victadol, Simultan, Riazole, Bactoprim, Subase, Tensazol, Cadmos, Retardon,

Also known as: Tramadol


Admadol (tramadol) is a pain medicine similar to an opioid. It acts in the central nervous system (CNS) to relieve pain.

Admadol is used to treat moderate to severe pain in adults.

The extended-release form of tramadol (Admadol ER) is for around-the-clock treatment of pain. Admadol ER is not for use on an as-needed basis for pain.


Usual Adult Dose for Pain:

Adults (17 years or older): 50 to 100 mg orally every 4 to 6 hours as needed for pain -For patients not requiring rapid onset of analgesic effect: Initial dose: 25 mg orally once a day; titrate in 25 mg increments every 3 days to reach a dose of 25 mg four times a day; thereafter increase by 50 mg as tolerated every 3 days Maximum dose: 400 mg per day.

Usual Adult Dose for Chronic Pain:

Extended-Release (ER): 18 years or older (tramadol-naive): 100 mg orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day For patients CURRENTLY receiving Immediate-Release (IR) Admadol: Initial Dose: Calculate 24-hour IR requirement and initiate with a total daily ER dose rounded down to the next lowest 100 mg increment orally once a day Conversion from OTHER Opioids: Discontinue all other around the clock opioid drugs prior to initiating therapy -Initial dose: 100 mg ER orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day.

Usual Geriatric Dose for Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Geriatric Dose for Chronic Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Pediatric Dose for Pain:

Admadol is not recommended for use in pediatric patients 17 years or older: See Adult Dose.

Detailed Admadol dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Admadol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Admadol if you are allergic to tramadol, or if you have:

severe asthma or breathing problems; a stomach or bowel obstruction (including paralytic ileus); if you have recently used alcohol, sedatives, tranquilizers, or narcotic medications; or if you have used an MAO inhibitor in the past 14 days (such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine).

Admadol should not be given to a child younger than 12 years old. Admadol ER should not be given to anyone younger than 18 years old.

Do not give Admadol to anyone younger than 18 years old who recently had surgery to remove the tonsils or adenoids.

Seizures have occurred in some people taking Admadol. Your seizure risk may be higher if you have ever had:

a head injury, epilepsy or other seizure disorder; drug or alcohol addiction; or a metabolic disorder.

To make sure Admadol is safe for you, tell your doctor if you have ever had:

breathing problems, sleep apnea; liver or kidney disease; urination problems; problems with your gallbladder, pancreas, or thyroid; a stomach disorder; or mental illness, or suicide attempt.

If you use tramadol during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks.

Ask a doctor before using tramadol if you are breastfeeding. Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.

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Breast feeding: a statement of the Infant Nutrition Subcommittee of the Paediatric Society of New Zealand. Neoplastic lesions affecting MYC expression are responsible for a drastic change in the number and the type of genes that are transcriptionally controlled by MYC, depending on differential promoter affinities. MicroRNAs (miRNAs) are endogenous small noncoding RNA molecules that negatively regulate gene expression. There appeared to be no particular merit of any of the treatments used (aspirin, prednisolone, and cold baths). One hundred consecutive patients undergoing surgery for primary hyperparathyroidism. Haplotype distribution of the multi-copy Y-STR loci DYS385, DYS459 and DYS464 in Chinese Han population. The identification of the isolates was performed by Multilocus variable-number tandem-repeat analysis (MLVA) technique and phylogenetic analysis of partial sequence of gene sec Y.

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Time-Course Analysis of Early Meiotic Prophase Events Informs Mechanisms of Homolog Pairing and Synapsis in Caenorhabditis elegans. Estimating COPD occurrence is perceived by the scientific community as a matter of increasing interest because of the worldwide diffusion of the disease. Ginseng has been used as an herbal medicine, widely used in Asian countries, for long time. International guidelines recommend that women with placenta praevia should be delivered by an experienced operator at a hospital with an on-site blood bank. The aim of this systematic literature review and meta-analysis was to evaluate the effect of negative adaptations to endurance training (i.e., a period of overreaching leading to attenuated performance) and positive adaptations (i.e., training leading to improved performance) on autonomic HR regulation in endurance-trained athletes.

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Two hundred and forty two consecutive adult patients with history of at least 2 unprovoked afebrile seizures were investigated for seizure patterns, aetiological and precipitating factors through history, physical examinations, laboratory tests and electroencephalography. Dark mitochondria often had more phosphorus, sulfur, and calcium than swollen, paler ones. Risk factors of short-term stroke recurrence in patients with minor ischemic cerebrovascular events. It has been shown that lidocaine administered as a bolus intra-arterially immediately prior to contrast media injections significantly decreased the pain experienced from aortofemoral arteriography. The aim of this study was to determine whether patient outcome is influenced by the method used to treat small single HCCs. For the microalgae, diversity was reduced by nutrient addition when grazer control was inefficient, but not when specialist microalgal grazers were present. ASM knock-out (ASMKO) mice are available as a model for NPD, but the lung pathology in these mice has not been adequately characterized.

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Investigation by the Method of INNO-LiPA of Primary Resistance to Lamivudine in Patients with Chronic Hepatitis B Who Have Not Used Antiviral Therapy. Substituent-dependent backward reaction in mechanofluorochromism of dibenzoylmethanatoboron difluoride derivatives. This article reviews recent developments with regard to multifactorial intervention trials for primary prevention of delirium. Cobalamin as an analytical tool for analysis of oxirane metabolites of 1,3-butadiene: development and validation of the method. These results suggest that MRI could serve as a screening examination for pulmonary artery stenosis after an arterial switch operation. This is the largest case series involving LSG in patients awaiting solid organ transplantation. This article is part of a Special Issue entitled: Xenobiotic nuclear receptors: New Tricks for An Old Dog, edited by Dr. In the inflamed synovium, 3-NT was found in the vascular smooth muscle and macrophages. Architects design building structures, although structural design is the profession of structural engineers.

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Anterior lumbar discectomy and fusion for acute cauda equina syndrome caused by recurrent disc prolapse: report of 3 cases. Many faculties like science, visual art, engineering and design must cooperate and work together toward that goal. Based on the ketamine model of NMDA receptor hypoactivity, therapeutic approaches designed to maintain a sustained increase in agonist activity at the glycine site of the what medicine can you take with zyrtec NMDA receptor have produced promising, although inconsistent, efficacy for negative symptoms. This family also seem essential in prostate cancer bone metastases, angiogenesis and androgen-independent progression. The locomotion training performed with departures from the flight documentation (ODFs) is described. Little data exist to guide treatment when this tumor extends to involve the structure of cavernous sinus.

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Early temporal variation of cerebral metabolites after human stroke. Our previous results have shown that inhibiting the small GTPase RhoB increased oxygenation of U87 human glioblastoma xenografts, in part, by regulating angiogenesis. Specificity was verified by RNAi experiments and by transfection with expression vectors for the intact CXCL16 and an intracellularly-truncated form of CXCL16. Major epigenetic events include methylation and acetylation of histones and regulatory factors, DNA methylation, and small non-coding RNAs. Methicillin-resistant Staphylococcus aureus (MRSA) bacteria have been responsible for substantial morbidity and mortality in hospitals because they usually have multidrug resistance. Hypothyroidism, diabetes and pleuropericarditis with antithyroideal, anti-insular, andtimytochondrial and antinuclear antibodies. Extraction and Purification of Polyphenols from Freeze-dried Berry Powder for the Treatment of Vascular Smooth Muscle Cells In Vitro.

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